(Q50474571)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17076667%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Complete alanine scanning of the two-component lantibiotic lacticin 3147: generating a blueprint for rational drug design (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17076667%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

1

1 reference

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21 December 2019

Colin Hill

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17076667%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Reynolds Paul Ross

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17076667%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Lucy H Deegan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17076667%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Elaine M Lawton

3

1 reference

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21 December 2019

Lorraine A Draper

4

1 reference

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21 December 2019

Paula M O'Connor

5

1 reference

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21 December 2019

language of work or name

English

0 references

publication date

1 November 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17076667%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

published in

Molecular Microbiology

1 reference

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21 December 2019

volume

62

1 reference

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21 December 2019

issue

3

1 reference

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21 December 2019

page(s)

735-747

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17076667%20AND%20SRC:MED&resulttype=core&format=json

Lipid II as a target for antibiotics

21 December 2019

cites work

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Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic.

21 January 2018

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Nisin, alone and combined with peptidoglycan-modulating antibiotics: activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci

21 January 2018

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Biosynthesis and mode of action of lantibiotics.

21 January 2018

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A food-grade approach for functional analysis and modification of native plasmids in Lactococcus lactis.

21 January 2018

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Bacteriocins: developing innate immunity for food

21 January 2018

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Bacterial lantibiotics: strategies to improve therapeutic potential.

21 January 2018

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Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147

21 January 2018

1 reference

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Sequence and analysis of the 60 kb conjugative, bacteriocin-producing plasmid pMRC01 from Lactococcus lactis DPC3147.

21 January 2018

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Lacticin 3147 displays activity in buffer against gram-positive bacterial pathogens which appear insensitive in standard plate assays.

21 January 2018

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Sequence analysis and membrane partitioning energies of alpha-helical antimicrobial peptides.

21 January 2018

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Posttranslational amino acid epimerization: enzyme-catalyzed isomerization of amino acid residues in peptide chains

21 January 2018

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Plantaricin W from Lactobacillus plantarum belongs to a new family of two-peptide lantibiotics

21 January 2018

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The structure of the lantibiotic lacticin 481 produced by Lactococcus lactis: location of the thioether bridges.

21 January 2018

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NMR study of mersacidin and lipid II interaction in dodecylphosphocholine micelles. Conformational changes are a key to antimicrobial activity

21 January 2018

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The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics

21 January 2018

1 reference

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Streptococcus rattus strain BHT produces both a class I two-component lantibiotic and a class II bacteriocin

21 January 2018

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Lantibiotics and microcins: polypeptides with unusual chemical diversity

21 January 2018

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The structure of the antimicrobial peptide Ac-RRWWRF-NH2 bound to micelles and its interactions with phospholipid bilayers

21 January 2018

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Mersacidin eradicates methicillin-resistant Staphylococcus aureus (MRSA) in a mouse rhinitis model.

21 January 2018

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Protein engineering of lantibiotics.

21 January 2018

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Each peptide of the two-component lantibiotic lacticin 3147 requires a separate modification enzyme for activity.

21 January 2018

1 reference

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Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05398.X

Sequential actions of the two component peptides of the lantibiotic lacticin 3147 explain its antimicrobial activity at nanomolar concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05398.X

Multiple activities in lantibiotics--models for the design of novel antibiotics?

21 January 2018

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High-resolution structures and dynamics of membrane protein--lipid complexes: a critique

21 January 2018

1 reference

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Lantibiotic structures as guidelines for the design of peptides that can be modified by lantibiotic enzymes.

21 January 2018

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Construction of an expression system for site-directed mutagenesis of the lantibiotic mersacidin

21 January 2018

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Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity

21 January 2018

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Lipid II-based antimicrobial activity of the lantibiotic plantaricin C.

21 January 2018

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Genetic analysis of a unique bacteriocin, Smb, produced by Streptococcus mutans GS5

21 January 2018

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The Effects of Hydrophobic Mismatch between Phosphatidylcholine Bilayers and Transmembrane α-Helical Peptides Depend on the Nature of Interfacially Exposed Aromatic and Charged Residues†

21 January 2018

1 reference

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