(Q50483251)

14 March 2018

title

Adiponectin mediated APPL1-AMPK signaling induces cell migration, MMP activation, and collagen remodeling in cardiac fibroblasts. (English)

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14 March 2018

author name string

Keith Dadson

1

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14 March 2018

Helen Chasiotis

2

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Sivaporn Wannaiampikul

3

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Rungsunn Tungtrongchitr

4

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Aimin Xu

5

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Gary Sweeney

6

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publication date

1 April 2014

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14 March 2018

Journal of Cellular Biochemistry

published in

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14 March 2018

volume

115

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issue

4

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page(s)

785-793

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Cardiac remodeling in obesity.

cites work

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Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells.

21 January 2018

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Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells.

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APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathway

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Adiponectin induces interleukin-6 production and its underlying mechanism in adult rat cardiac fibroblasts

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An APPL1-AMPK signaling axis mediates beneficial metabolic effects of adiponectin in the heart.

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BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity

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Site-specific cellular functions of MT1-MMP.

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21 January 2018

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APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

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A look between the cardiomyocytes: the extracellular matrix in heart failure

21 January 2018

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Direct effects of adipokines on the heart: focus on adiponectin

21 January 2018

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New evidence for a critical role of elastin in calcification of native heart valves: immunohistochemical and ultrastructural study with literature review.

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Coordinate action of membrane-type matrix metalloproteinase-1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion

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Increased expression and cell surface localization of MT1-MMP plays a role in stimulation of MMP-2 activity by leptin in neonatal rat cardiac myofibroblasts

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21 January 2018

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21 January 2018

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21 January 2018

1 reference

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21 January 2018

1 reference

Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells

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Myofibroblast-mediated mechanisms of pathological remodelling of the heart

21 January 2018

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Cross talk between cardiac myocytes and fibroblasts: from multiscale investigative approaches to mechanisms and functional consequences

21 January 2018

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Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCB.24722

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14 March 2018

PubMed ID

24255018

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14 March 2018