(Q50505059)

14 March 2018

title

Chinese hamster AP endonuclease operates by a two-metal ion assisted catalytic mechanism. (English)

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14 March 2018

author name string

Mandula Borjigin

series ordinal

1

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14 March 2018

Pablo Arenaz

series ordinal

2

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14 March 2018

Boguslaw Stec

series ordinal

3

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14 March 2018

language of work or name

English

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publication date

28 December 2011

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14 March 2018

number of pages

6

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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14 March 2018

volume

586

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14 March 2018

issue

3

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14 March 2018

page(s)

242-247

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14 March 2018

Rate of depurination of native deoxyribonucleic acid

cites work

1 reference

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Life without DNA repair

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Mechanism of DNA cleavage and substrate recognition by a bovine apurinic endonuclease.

21 January 2018

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The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites

21 January 2018

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The role of Mg2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis.

21 January 2018

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DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

21 January 2018

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Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism

21 January 2018

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Enzymatic mechanism of human apurinic/apyrimidinic endonuclease against a THF AP site model substrate

21 January 2018

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Conformational transitions in human AP endonuclease 1 and its active site mutant during abasic site repair.

21 January 2018

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Molecular cloning, sequence and structure analysis of hamster apurinic/apyrimidinic endonuclease (chAPE1) gene

21 January 2018

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Chinese hamster apurinic/apyrimidinic endonuclease (chAPE1) expressed in sf9 cells reveals that its endonuclease activity is regulated by phosphorylation

21 January 2018

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A two-metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate

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Inhibition of Ape1 nuclease activity by lead, iron, and cadmium

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Increasing the precision of comparative models with YASARA NOVA-a self-parameterizing force field

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Asparagine 212 is essential for abasic site recognition by the human DNA repair endonuclease HAP1

21 January 2018

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Substitution of Asp-210 in HAP1 (APE/Ref-1) eliminates endonuclease activity but stabilises substrate binding.

21 January 2018

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A "moving metal mechanism" for substrate cleavage by the DNA repair endonuclease APE-1.

21 January 2018

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Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product

21 January 2018

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Substrate binding by human apurinic/apyrimidinic endonuclease indicates a Briggs-Haldane mechanism

21 January 2018

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Characterization of Mg2+ binding to the DNA repair protein apurinic/apyrimidic endonuclease 1 via solid-state 25Mg NMR spectroscopy.

21 January 2018

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An equivalent metal ion in one- and two-metal-ion catalysis

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Structural basis of HutP-mediated anti-termination and roles of the Mg2+ ion and L-histidine ligand

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21 January 2018

Identifiers

DOI

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14 March 2018

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14 March 2018