(Q50561813)

15 March 2018

title

A phase 1 study of ABT-806 in subjects with advanced solid tumors. (English)

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15 March 2018

Leena Gandhi

4

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David A Reardon

2

object named as

David A Reardon

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15 March 2018

James M Cleary

1

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15 March 2018

Nilofer Azad

3

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15 March 2018

Geoffrey I Shapiro

5

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15 March 2018

Jorge Chaves

6

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15 March 2018

Michelle Pedersen

7

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15 March 2018

Peter Ansell

8

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15 March 2018

William Ames

9

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15 March 2018

Hao Xiong

10

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15 March 2018

Wijith Munasinghe

11

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15 March 2018

Matt Dudley

12

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15 March 2018

Edward B Reilly

13

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15 March 2018

Kyle Holen

14

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15 March 2018

Rod Humerickhouse

15

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15 March 2018

publication date

17 April 2015

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15 March 2018

Investigational New Drugs

published in

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15 March 2018

volume

33

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15 March 2018

issue

3

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15 March 2018

page(s)

671-678

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15 March 2018

EGFR antagonists in cancer treatment

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Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer

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Pharmacokinetic and pharmacodynamic properties of EGFR inhibitors under clinical investigation.

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Targeting of a conformationally exposed, tumor-specific epitope of EGFR as a strategy for cancer therapy

21 January 2018

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Therapeutic anti-EGFR antibody 806 generates responses in murine de novo EGFR mutant-dependent lung carcinomas

21 January 2018

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A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors

21 January 2018

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EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small-cell lung cancer: analysis of data from the phase 3 FLEX study

21 January 2018

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Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR

21 January 2018

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Safety, pharmacokinetics, and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer

21 January 2018

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Epidermal Growth Factor Receptor in Glioma: Signal Transduction, Neuropathology, Imaging, and Radioresistance

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Structural, Biochemical, and Clinical Characterization of Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations in Lung Cancer

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A case of penile squamous cell carcinoma treated with a combination of antiepidermal growth factor receptor antibody and chemotherapy.

21 January 2018

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Epidermal growth factor receptor-targeted therapy in squamous cell carcinoma of the penis: a report of 3 cases

21 January 2018

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The epidermal growth factor receptor is frequently overexpressed in penile squamous cell carcinomas: a tissue microarray and digital image analysis study of 112 cases

21 January 2018

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Epidermal growth factor receptor-targeted therapy in locally advanced or metastatic squamous cell carcinoma of the penis

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Epidermal growth factor receptor (EGFR)-RAS signaling pathway in penile squamous cell carcinoma

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Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck.

21 January 2018

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Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin.

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Tyrosine kinases as targets for cancer therapy

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Pharmacokinetics of cetuximab after administration of escalating single dosing and weekly fixed dosing in patients with solid tumors

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12 December 2020

Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR.

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12 December 2020

Activated extracellular signal-regulated kinases: association with epidermal growth factor receptor/transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments

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12 December 2020

Impact and management of skin toxicity associated with anti-epidermal growth factor receptor therapy: survey results

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12 December 2020

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12 December 2020

Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers

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Identifiers

DOI

1 reference

15 March 2018

1 reference

15 March 2018