(Q50576529)

15 March 2018

title

Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin. (English)

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15 March 2018

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Dale L Barnard

1

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15 March 2018

Craig W Day

2

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15 March 2018

Kevin Bailey

3

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15 March 2018

Matthew Heiner

4

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15 March 2018

Robert Montgomery

5

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15 March 2018

Larry Lauridsen

6

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15 March 2018

Scott Winslow

7

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15 March 2018

Justin Hoopes

8

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15 March 2018

Joseph K-K Li

9

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15 March 2018

Jongdae Lee

10

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15 March 2018

Dennis A Carson

11

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15 March 2018

Howard B Cottam

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Robert W Sidwell

13

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15 March 2018

publication date

24 March 2006

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15 March 2018

published in

Antiviral Research

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15 March 2018

volume

71

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15 March 2018

page(s)

53-63

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15 March 2018

issue

1

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15 March 2018

Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients

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12 December 2020

The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase

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Benzamide riboside induced mitochondrial mediated apoptosis in human lung cancer H520 cells

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Pleiotropic mechanisms of ribavirin antiviral activities

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Persistence of lung inflammation and lung cytokines with high-resolution CT abnormalities during recovery from SARS

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Contact hypersensitivity responses following ribavirin treatment in vivo are influenced by type 1 cytokine polarization, regulation of IL-10 expression, and costimulatory signaling.

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Is the anti-psychotic, 10-(3-(dimethylamino)propyl)phenothiazine (promazine), a potential drug with which to treat SARS infections? Lack of efficacy of promazine on SARS-CoV replication in a mouse model

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Ribavirin in the treatment of severe acute respiratory syndrome (SARS)

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Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus

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Advancements in the battle against severe acute respiratory syndrome

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Medical treatment of viral pneumonia including SARS in immunocompetent adult

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Immunosuppression minimization: current and future trends in transplant immunosuppression

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Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings.

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In vitro activity of expanded-spectrum pyridazinyl oxime ethers related to pirodavir: novel capsid-binding inhibitors with potent antipicornavirus activity

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New antiviral drugs, vaccines and classic public health interventions against SARS coronavirus

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Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China

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Mycophenolic acid inhibits inosine 5'-monophosphate dehydrogenase and suppresses production of pro-inflammatory cytokines, nitric oxide, and LDH in macrophages

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Adverse effects of ribavirin and outcome in severe acute respiratory syndrome: experience in two medical centers

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Expression of bcl-2 protein in chronic hepatitis C: effect of interferon alpha 2b with ribavirin therapy

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Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice

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Mechanisms of action of ribavirin in antiviral therapies

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Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target

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Structure-based preliminary analysis of immunity and virulence of SARS coronavirus.

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Recent progress in antiviral chemotherapy for respiratory syncytial virus infections

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Ribavirin and interferon-beta synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines.

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Toxicity and efficacy of benzamide riboside in cancer chemotherapy models

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12 December 2020

Ribavirin inhibits DNA, RNA, and protein synthesis in PHA-stimulated human peripheral blood mononuclear cells: possible explanation for therapeutic efficacy in patients with chronic HCV infection

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Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus

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Increased sensitivity of SARS-coronavirus to a combination of human type I and type II interferons.

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A semi-automated neutral red based chemosensitivity assay for drug screening

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Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway

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Severe acute respiratory syndrome (SARS) and coronavirus testing--United States, 2003

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Mycophenolate mofetil inhibits differentiation, maturation and allostimulatory function of human monocyte-derived dendritic cells

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Severe acute respiratory syndrome-related coronavirus is inhibited by interferon- alpha

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12 December 2020

Temporal relationship of viral load, ribavirin, interleukin (IL)-6, IL-8, and clinical progression in patients with severe acute respiratory syndrome

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Immunosuppressive drugs: the first 50 years and a glance forward

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Inhibition of severe acute respiratory syndrome-associated coronavirus (SARSCoV) by calpain inhibitors and beta-D-N4-hydroxycytidine

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Severe acute respiratory syndrome-associated coronavirus in lung tissue

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Development of a standard treatment protocol for severe acute respiratory syndrome

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HIV protease inhibitor nelfinavir inhibits replication of SARS-associated coronavirus

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12 December 2020

Ribavirin in the treatment of SARS: A new trick for an old drug?

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12 December 2020

In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds.

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12 December 2020

Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice

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12 December 2020

Ribavirin inhibits viral-induced macrophage production of TNF, IL-1, the procoagulant fgl2 prothrombinase and preserves Th1 cytokine production but inhibits Th2 cytokine response.

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12 December 2020

Clinical manifestations and inflammatory cytokine responses in patients with severe acute respiratory syndrome.

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12 December 2020

10.1016/J.ANTIVIRAL.2006.03.001

Identifiers

DOI

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15 March 2018

PubMed ID

16621037

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15 March 2018