(Q50667669)

17 March 2018

title

Engineering of the LysR family transcriptional regulator FkbR1 and its target gene to improve ascomycin production. (English)

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17 March 2018

author name string

Kejing Song

1

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17 March 2018

Liang Wei

2

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17 March 2018

Jiao Liu

3

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17 March 2018

Junhua Wang

4

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17 March 2018

Haishan Qi

5

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17 March 2018

Jianping Wen

6

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17 March 2018

language of work or name

English

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publication date

27 March 2017

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17 March 2018

Applied Microbiology and Biotechnology

published in

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17 March 2018

volume

101

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17 March 2018

issue

11

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17 March 2018

page(s)

4581-4592

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17 March 2018

https://scigraph.springernature.com/pub.10.1007/s00253-017-8242-4

exact match

0 references

cites work

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1 reference

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The Streptococcus iniae transcriptional regulator CpsY is required for protection from neutrophil-mediated killing and proper growth in vitro

21 January 2018

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A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier protein (MatC) in Rhizobium trifolii--cloning, sequencing, and expression of the enzymes in Escherichia coli

21 January 2018

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Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate

21 January 2018

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Trends in the biosynthesis and production of the immunosuppressant tacrolimus (FK506).

21 January 2018

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Regulation of secondary metabolism in streptomycetes

21 January 2018

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Identification and utility of FdmR1 as a Streptomyces antibiotic regulatory protein activator for fredericamycin production in Streptomyces griseus ATCC 49344 and heterologous hosts

21 January 2018

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Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme

21 January 2018

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FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis

21 January 2018

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The pathway-specific regulator AveR from Streptomyces avermitilis positively regulates avermectin production while it negatively affects oligomycin biosynthesis

21 January 2018

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Genome-scale metabolic network guided engineering of Streptomyces tsukubaensis for FK506 production improvement

21 January 2018

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TcyR regulates L-cystine uptake via the TcyABC transporter in Streptococcus mutans

21 January 2018

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The LysR-type virulence activator AphB regulates the expression of genes in Vibrio cholerae in response to low pH and anaerobiosis

21 January 2018

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The mycobacterial LysR-type regulator OxyS responds to oxidative stress and negatively regulates expression of the catalase-peroxidase gene

21 January 2018

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Sigma factor WhiGch positively regulates natamycin production in Streptomyces chattanoogensis L10.

21 January 2018

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Increasing Avermectin Production in Streptomyces avermitilis by Manipulating the Expression of a Novel TetR-Family Regulator and Its Target Gene Product

21 January 2018

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The LysR-type transcriptional regulator YofA controls cell division through the regulation of expression of ftsW in Bacillus subtilis

21 January 2018

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21 January 2018

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Positive feedback regulation of stgR expression for secondary metabolism in Streptomyces coelicolor

21 January 2018

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21 January 2018

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Roles of fkbN in positive regulation and tcs7 in negative regulation of FK506 biosynthesis in Streptomyces sp. strain KCTC 11604BP

21 January 2018

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Antimalarial effects of macrolactones related to FK520 (ascomycin) are independent of the immunosuppressive properties of the compounds

21 January 2018

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Beta-glucuronidase as a sensitive and versatile reporter in actinomycetes.

21 January 2018

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Molecular and structural considerations of TF-DNA binding for the generation of biologically meaningful and accurate phylogenetic footprinting analysis: the LysR-type transcriptional regulator family as a study model.

21 January 2018

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A pathway-specific transcriptional activator regulates late steps of clavulanic acid biosynthesis in Streptomyces clavuligerus

21 January 2018

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Molecular mechanism of the regulation of Bacillus subtilis gltAB expression by GltC

21 January 2018

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Integration of parallel 13 C-labeling experiments and in silico pathway analysis for enhanced production of ascomycin

21 January 2018

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GamR, the LysR-Type Galactose Metabolism Regulator, Regulates hrp Gene Expression via Transcriptional Activation of Two Key hrp Regulators, HrpG and HrpX, in Xanthomonas oryzae pv. oryzae

21 January 2018

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Genetically engineered analogs of ascomycin for nerve regeneration

21 January 2018

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Transcriptional coupling between the divergent promoters of a prototypic LysR-type regulatory system, the ilvYC operon of Escherichia coli

21 January 2018

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Identification of transcriptional activators for thienamycin and cephamycin C biosynthetic genes within the thienamycin gene cluster from Streptomyces cattleya

21 January 2018

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Angucyclines as signals modulate the behaviors of Streptomyces coelicolor.

21 January 2018

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The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00253-017-8242-4

A LysR-type regulator, CidR, is required for induction of the Staphylococcus aureus cidABC operon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-017-8242-4

FkbN and Tcs7 are pathway-specific regulators of the FK506 biosynthetic gene cluster in Streptomyces tsukubaensis L19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-017-8242-4

SlnR is a positive pathway-specific regulator for salinomycin biosynthesis in Streptomyces albus.

21 January 2018

1 reference

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10.1007/S00253-017-8242-4

21 January 2018

Identifiers

DOI

1 reference

17 March 2018

PubMed ID

28349163

1 reference

17 March 2018