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Thymic selection and lineage commitment of CD4(+)Foxp3(+) regulatory T lymphocytes.
scientific article published in January 2010
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20800824
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20800824%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
title
Thymic selection and lineage commitment of CD4(+)Foxp3(+) regulatory T lymphocytes
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20800824
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20800824%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
main subject
cell fate commitment
1 reference
based on heuristic
inferred from title
author
Joost P.M. van Meerwijk
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20800824
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20800824%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
author name string
Paola Romagnoli
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20800824
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20800824%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
publication date
1 January 2010
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20800824
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20800824%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
published in
Progress in Molecular Biology and Translational Science
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20800824
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20800824%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
volume
92
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20800824
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20800824%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
page(s)
251-277
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20800824
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20800824%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
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Murine CD8+ regulatory T lymphocytes: the new era.
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Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice
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Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells
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The physiological role of regulatory T cells in the prevention of autoimmunity: the function of the thymus in the generation of the regulatory T cell subset
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Reentry of T cells to the adult thymus is restricted to activated T cells
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Peripheral T cell lymphopenia and concomitant enrichment in naturally arising regulatory T cells: the case of the pre-Talpha gene-deleted mouse
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Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes
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OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset
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7 January 2021
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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
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Control of regulatory T cell development by the transcription factor Foxp3
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Foxp3-dependent programme of regulatory T-cell differentiation
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Preferential recognition of self antigens despite normal thymic deletion of CD4(+)CD25(+) regulatory T cells
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Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.
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7 January 2021
based on heuristic
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CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory T cells mediate maternal tolerance to the fetus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors
1 reference
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https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
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Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Segmented filamentous bacteria in a defined bacterial cocktail induce intestinal inflammation in SCID mice reconstituted with CD45RBhigh CD4+ T cells
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cells
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
miR-181a is an intrinsic modulator of T cell sensitivity and selection
1 reference
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https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
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In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells
1 reference
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7 January 2021
based on heuristic
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H-2 antigens of the thymus determinelymphocyte specificity
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
The role of thymic epithelium in the establishment of transplantation tolerance
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigens
1 reference
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https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Origin of regulatory T cells with known specificity for antigen
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells
1 reference
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https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage
1 reference
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https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Agonist ligands expressed by thymic epithelium enhance positive selection of regulatory T lymphocytes from precursors with a normally diverse TCR repertoire
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
The thymic compartment responsible for positive selection of CD4+ T cells
1 reference
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https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
1 reference
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https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dissociation of thymic positive and negative selection in transgenic mice expressing major histocompatibility complex class I molecules exclusively on thymic cortical epithelial cells
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Positive selection of CD4+ thymocytes controlled by MHC class II gene products
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Positive selection of the T cell repertoire: where and when does it occur?
1 reference
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https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus
1 reference
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https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of a novel MHC-encoded serine peptidase highly expressed by cortical epithelial cells of the thymus
1 reference
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7 January 2021
based on heuristic
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Differential gene expression in CD3epsilon- and RAG1-deficient thymuses: definition of a set of genes potentially involved in thymocyte maturation.
1 reference
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7 January 2021
based on heuristic
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Regulation of CD8+ T cell development by thymus-specific proteasomes
1 reference
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https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differentiation of regulatory Foxp3+ T cells in the thymic cortex
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
The impact of negative selection on thymocyte migration in the medulla.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Clonal deletion versus clonal anergy: the role of the thymus in inducing self tolerance
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dependence of self-tolerance on TRAF6-directed development of thymic stroma
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Generalized multi-organ autoimmunity in CCR7-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A central role for central tolerance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aire
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positional cloning of the APECED gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Projection of an immunological self shadow within the thymus by the aire protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aire-deficient C57BL/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aire regulates negative selection of organ-specific T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cellular mechanism of Aire control of T cell tolerance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular signature of recent thymic selection events on effector and regulatory CD4+ T lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct functional capacities of mouse thymic and splenic dendritic cell populations.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Presentation and intercellular transfer of self antigen within the thymic microenvironment: expression of the E alpha peptide-I-Ab complex by isolated thymic stromal cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Does T-cell tolerance require a dedicated antigen-presenting cell?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IMMUNOGENETIC CONSEQUENCES OF VASCULAR ANASTOMOSES BETWEEN BOVINE TWINS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptide specificity of thymic selection of CD4+CD25+ T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dendritic cells in the thymus contribute to T-regulatory cell induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymus-blood protein interactions are highly effective in negative selection and regulatory T cell induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiency of the Src homology region 2 domain-containing phosphatase 1 (SHP-1) causes enrichment of CD4+CD25+ regulatory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased numbers of thymic and peripheral CD4+ CD25+Foxp3+ cells in the absence of CD5 signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+ T-cell development in a mouse expressing a transgenic TCR derived from a Treg
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TCR-dependent differentiation of thymic Foxp3+ cells is limited to small clonal sizes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intraclonal competition limits the fate determination of regulatory T cells in the thymus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Several different cell surface molecules control negative selection of medullary thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 signaling in T regulatory precursors requires p56lck and rafts integrity to stabilize the Foxp3 message
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A costimulatory function for T cell CD40.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD40 ligand-transduced co-stimulation of T cells in the development of helper function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD40/CD40L interaction regulates CD4+CD25+ T reg homeostasis through dendritic cell-produced IL-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunopathology of interleukin (IL) 2-deficient mice: thymus dependence and suppression by thymus-dependent cells with an intact IL-2 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normal lymphoid homeostasis and lack of lethal autoimmunity in mice containing mature T cells with severely impaired IL-2 receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A function for interleukin 2 in Foxp3-expressing regulatory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-2Rbeta links IL-2R signaling with Foxp3 expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ontogeny, function, and peripheral homeostasis of regulatory T cells in the absence of interleukin-7
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inducing and expanding regulatory T cell populations by foreign antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation and function of NF-kappaB transcription factors in the immune system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mature T cells depend on signaling through the IKK complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early events in the thymus affect the balance of effector and regulatory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic control of thymic development of CD4+CD25+FoxP3+ regulatory T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An MHC-linked locus modulates thymic differentiation of CD4+CD25+Foxp3+ regulatory T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Self-reactivity in thymic double-positive cells commits cells to a CD8 alpha alpha lineage with characteristics of innate immune cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of pre- and postselection TCRalphabeta+ intraepithelial lymphocyte precursors in the thymus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The biology of NKT cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell population
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymocyte-thymocyte interaction for efficient positive selection and maturation of CD4 T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymic selection pathway regulates the effector function of CD4 T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation of PLZF+ CD4+ T cells via MHC class II-dependent thymocyte-thymocyte interaction is a physiological process in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992010-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1877-1173(10)92010-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20800824
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20800824%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
PubMed publication ID
20800824
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20800824
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20800824%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
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