(Q50675328)

17 March 2018

title

Tyrosine 687 phosphorylated Alzheimer's amyloid precursor protein is retained intracellularly and exhibits a decreased turnover rate. (English)

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17 March 2018

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1

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Sandra I. Vieira

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Jens Wiltfang

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17 March 2018

author name string

Hermann Esselmann

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Edgar F da Cruz e Silva

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Odete A B da Cruz e Silva

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publication date

1 January 2007

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17 March 2018

Neurodegenerative Diseases

published in

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17 March 2018

volume

4

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issue

2-3

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17 March 2018

page(s)

78-87

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17 March 2018

The role of APP processing and trafficking pathways in the formation of amyloid beta-protein

cites work

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Expression analysis of BACE2 in brain and peripheral tissues

21 January 2018

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

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Gamma-secretase complex assembly within the early secretory pathway

21 January 2018

1 reference

Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

21 January 2018

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PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin

21 January 2018

1 reference

Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch

21 January 2018

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Regulated cleavage of Alzheimer beta-amyloid precursor protein in the absence of the cytoplasmic tail

21 January 2018

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Protein phosphorylation regulates relative utilization of processing pathways for Alzheimer beta/A4 amyloid precursor protein

21 January 2018

1 reference

Effect of cell density on intracellular levels of the Alzheimer's amyloid precursor protein

21 January 2018

1 reference

Monitoring protein phosphatase 1 isoform levels as a marker for cellular stress

21 January 2018

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Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells.

21 January 2018

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Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides

21 January 2018

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

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Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses

21 January 2018

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Signal transduction therapeutics: relevance for Alzheimer's disease

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1159/000101831

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17 March 2018

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17 March 2018