(Q50706209)

English

Valproic acid reduces neuritic plaque formation and improves learning deficits in APP(Swe) /PS1(A246E) transgenic mice via preventing the prenatal hypoxia-induced down-regulation of neprilysin.

scientific article published on 2 December 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/24289518

Valproic acid reduces neuritic plaque formation and improves learning deficits in APP(Swe) /PS1(A246E) transgenic mice via preventing the prenatal hypoxia-induced down-regulation of neprilysin. (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/24289518

author name string

Zheng Wang

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

Xiao-Jie Zhang

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

Ting Li

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

Jia Li

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

Yu Tang

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

Weidong Le

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

publication date

2 December 2013

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/24289518

CNS Neuroscience & Therapeutics

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

20

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

209-217

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

Etiology of sporadic Alzheimer's disease: somatostatin, neprilysin, and amyloid beta peptide

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Molecular and cellular mechanisms for Alzheimer's disease: understanding APP metabolism

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

The amyloid precursor protein: beyond amyloid

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Neprilysin regulates amyloid Beta peptide levels

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease.

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the "LEARn" model (latent early-life associated regulation) may explain the triggering of AD.

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Neuropsychiatric and behavioral aspects of trisomy 21.

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Hypoxia signaling to genes: significance in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

The blood-brain barrier: an overview: structure, regulation, and clinical implications

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Update on hypertension and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Hypoxia increases Abeta generation by altering beta- and gamma-cleavage of APP.

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Prenatal hypoxia may aggravate the cognitive impairment and Alzheimer's disease neuropathology in APPSwe/PS1A246E transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Hypoxia-induced down-regulation of neprilysin by histone modification in mouse primary cortical and hippocampal neurons

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Pathological role of hypoxia in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Effects of hypoxia and oxidative stress on expression of neprilysin in human neuroblastoma cells and rat cortical neurones and astrocytes

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy.

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Atherosclerosis and AD: analysis of data from the US National Alzheimer's Coordinating Center

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Relation of cerebral infarctions to dementia and cognitive function in older persons

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Amyloid-degrading enzymes as therapeutic targets in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation.

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe.

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

The new generation of GABA enhancers. Potential in the treatment of epilepsy

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Valproic acid attenuates neuronal loss in the brain of APP/PS1 double transgenic Alzheimer's disease mice model.

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Valproate reduces tau phosphorylation via cyclin-dependent kinase 5 and glycogen synthase kinase 3 signaling pathways

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Valproic acid stimulates clusterin expression in human astrocytes: Implications for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Valproic acid enhances microglial phagocytosis of amyloid-beta(1-42).

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Recovery of learning and memory is associated with chromatin remodelling

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

A comparative study of modified Bielschowsky, Bodian and thioflavin S stains on Alzheimer's neurofibrillary tangles.

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Cerebrospinal fluid neprilysin is reduced in prodromal Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Neprilysin and amyloid beta peptide degradation

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Transcriptional regulation of APH-1A and increased gamma-secretase cleavage of APP and Notch by HIF-1 and hypoxia.

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Effect of ischemic neuronal insults on amyloid precursor protein processing

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Histone deacetylases: focus on the nervous system

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Presenilin 1 gene silencing by S‐adenosylmethionine: a treatment for Alzheimer disease?

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Enhanced clearance of Abeta in brain by sustaining the plasmin proteolysis cascade

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Valproic acid inhibits Abeta production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models

1 reference

https://api.crossref.org/works/10.1111%2FCNS.12186

21 January 2018

Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24289518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dependence of histone modifications and gene expression on DNA hypermethylation in cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24289518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/24289518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Impact of treatment with acetylcholinesterase inhibitors, valproic acid and antipsychotics on aggressive behaviour in Alzheimer's type dementia]

1 reference

https://pubmed.ncbi.nlm.nih.gov/24289518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the human CD10/neutral endopeptidase 24.11 promoter region: two separate regulatory elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/24289518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific expression of rat neutral endopeptidase (neprilysin) mRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/24289518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/CNS.12186

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493036&resulttype=core&format=json

14 May 2020

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