(Q50732939)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23219959%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

title

Neural differentiation of Fragile X human Embryonic Stem Cells reveals abnormal patterns of development despite successful neurogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23219959%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

1 reference

human embryonic stem cell

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23219959%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

2

Menahem Segal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23219959%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

3

Dalit Ben-Yosef

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23219959%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

language of work or name

English

0 references

publication date

5 December 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23219959%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

published in

Developmental Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23219959%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

volume

374

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23219959%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23219959%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

page(s)

32-45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23219959%20AND%20SRC:MED&resulttype=core&format=json

Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain.

19 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Correlates across the structural, functional, and molecular phenotypes of fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

The pathophysiology of fragile X (and what it teaches us about synapses)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Normal Neurogenesis but Abnormal Gene Expression in Human Fragile X Cortical Progenitor Cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Bicaudal-D regulates fragile X mental retardation protein levels, motility, and function during neuronal morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Inhibition of notch signaling in human embryonic stem cell-derived neural stem cells delays G1/S phase transition and accelerates neuronal differentiation in vitro and in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

FMRP involvement in formation of synapses among cultured hippocampal neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Differentiation of neuronal cells in fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Altered differentiation of neural stem cells in fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Murine hippocampal neurons expressing Fmr1 gene premutations show early developmental deficits and late degeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

BMP, Wnt and Hedgehog signals: how far can they go?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Derivation of Embryonic Stem-Cell Lines from Human Blastocysts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Fragile X syndrome: from molecular genetics to therapy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Generation and characterization of FMR1 knockout zebrafish

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Human embryonic stem cells carrying mutations for severe genetic disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

The role of Pax6 in forebrain development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Origins of epilepsy in fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Fragile-X chromosome and learning disability.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Dendritic spine structural anomalies in fragile-X mental retardation syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Extracellular matrix and the neural stem cell niche

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Developmental expression of Xenopus fragile X mental retardation-1 gene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Preimplantation genetic diagnosis for fragile X syndrome using multiplex nested PCR.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

The generation of a conditional Fmr1 knock out mouse model to study Fmrp function in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Drosophila fragile X protein, DFXR, regulates neuronal morphology and function in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Abnormal development of dendritic spines in FMR1 knock-out mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Marked differences in differentiation propensity among human embryonic stem cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Developmental expression of FMRP in the astrocyte lineage: implications for fragile X syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Roles of Wnt proteins in neural development and maintenance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

The pathophysiology of fragile x syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Neural progenitor cells from an adult patient with fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

SoxB1 transcription factors restrict organizer gene expression by repressing multiple events downstream of Wnt signalling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

DNA methylation represses FMR-1 transcription in fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Group I metabotropic glutamate receptor antagonists alter select behaviors in a mouse model for fragile X syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Embryonic stem cell lines derived from human blastocysts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

The effect of an mGluR5 inhibitor on procedural memory and avoidance discrimination impairments in Fmr1 KO mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

New perspectives on the biology of fragile X syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Timing of the absence of FMR1 expression in full mutation chorionic villi.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

The fragile X syndrome: from molecular genetics to neurobiology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Development and differentiation of neural rosettes derived from human embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Differentiation of neuroepithelia from human embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Notch signaling downstream of foxD5 promotes neural ectodermal transcription factors that inhibit neural differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031

Differentiation of neural precursors and dopaminergic neurons from human embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.11.031