(Q50912096)

25 March 2018

title

Deubiquitinating enzyme USP22 positively regulates c-Myc stability and tumorigenic activity in mammalian and breast cancer cells. (English)

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25 March 2018

author name string

Dongyeon Kim

1

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25 March 2018

Ahyoung Hong

2

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25 March 2018

Hye In Park

3

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25 March 2018

Woo Hyun Shin

4

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25 March 2018

Lang Yoo

5

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25 March 2018

Seo Jeong Jeon

6

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25 March 2018

Kwang Chul Chung

7

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25 March 2018

publication date

4 February 2017

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25 March 2018

Journal of Cellular Physiology

published in

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25 March 2018

volume

232

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25 March 2018

issue

12

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25 March 2018

page(s)

3664-3676

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25 March 2018

Transcriptional regulation and transformation by Myc proteins

cites work

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The epigenetic modifier JMJD6 is amplified in mammary tumors and cooperates with c-Myc to enhance cellular transformation, tumor progression, and metastasis

21 January 2018

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USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1

21 January 2018

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Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance.

21 January 2018

1 reference

ELL targets c-Myc for proteasomal degradation and suppresses tumour growth

21 January 2018

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c-Myc target genes involved in cell growth, apoptosis, and metabolism

21 January 2018

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Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival

21 January 2018

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Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

21 January 2018

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21 January 2018

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Choosing the right cell line for breast cancer research

21 January 2018

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Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination

21 January 2018

1 reference

Assembly of b/HLH/z proteins c-Myc, Max, and Mad1 with cognate DNA: importance of protein-protein and protein-DNA interactions

21 January 2018

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Expression patterns of USP22 and potential targets BMI-1, PTEN, p-AKT in non-small-cell lung cancer.

21 January 2018

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Inhibition of Ubiquitin-specific Peptidase 8 Suppresses Growth of Gefitinib-resistant Non-small Cell Lung Cancer Cells by Inducing Apoptosis

21 January 2018

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The F-box protein FBXO7 positively regulates bone morphogenetic protein-mediated signaling through Lys-63-specific ubiquitination of neurotrophin receptor-interacting MAGE (NRAGE).

21 January 2018

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Deubiquitinating enzymes as cellular regulators

21 January 2018

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Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1.

21 January 2018

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USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development.

21 January 2018

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Aberrant expression of USP22 is associated with liver metastasis and poor prognosis of colorectal cancer

21 January 2018

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Silencing USP22 by asymmetric structure of interfering RNA inhibits proliferation and induces cell cycle arrest in bladder cancer cells

21 January 2018

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FBXO32 Targets c-Myc for Proteasomal Degradation and Inhibits c-Myc Activity

21 January 2018

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Ubiquitin-specific peptidase 22 functions and its involvement in disease

21 January 2018

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USP2a activation of MYC in prostate cancer

21 January 2018

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Deubiquitinases and the new therapeutic opportunities offered to cancer

21 January 2018

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USP22 is useful as a novel molecular marker for predicting disease progression and patient prognosis of oral squamous cell carcinoma

21 January 2018

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Polyubiquitin chains: polymeric protein signals

21 January 2018

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The ubiquitin-specific protease USP28 is required for MYC stability

21 January 2018

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SIRT3 inhibits prostate cancer by destabilizing oncoprotein c-MYC through regulation of the PI3K/Akt pathway

21 January 2018

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MYC is a metastasis gene for non-small-cell lung cancer

21 January 2018

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MYC overexpression and poor prognosis in sporadic breast cancer with BRCA1 deficiency

21 January 2018

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USP22 regulates oncogenic signaling pathways to drive lethal cancer progression

21 January 2018

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

21 January 2018

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High USP22 expression indicates poor prognosis in hepatocellular carcinoma.

21 January 2018

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Ubiquitin and ubiquitin-like proteins as multifunctional signals

21 January 2018

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The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

21 January 2018

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21 January 2018

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Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer

21 January 2018

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Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

21 January 2018

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Ubiquitin-specific protease 22: a novel molecular biomarker in cervical cancer prognosis and therapeutics

21 January 2018

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The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.25841

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25 March 2018

PubMed ID

28160502

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25 March 2018