(Q50943688)

25 March 2018

title

A spatially and temporally restricted mouse model of soft tissue sarcoma. (English)

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17

Ralph Weissleder

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14

Stanley J Korsmeyer

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25 March 2018

Tyler Jacks

18

Tyler Jacks

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25 March 2018

David Kirsch

1

David G Kirsch

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25 March 2018

Jan Grimm

4

Jan Grimm

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25 March 2018

Philip M Santiago

5

Philip M Santiago

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25 March 2018

Sam S Yoon

15

Sam S Yoon

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25 March 2018

G Petur Nielsen

7

G Petur Nielsen

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25 March 2018

Osamu Takeuchi

11

Osamu Takeuchi

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25 March 2018

author name string

Daniela M Dinulescu

2

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25 March 2018

John B Miller

3

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Nathan P Young

6

1 reference

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Bradley J Quade

8

1 reference

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Christopher J Chaber

9

1 reference

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Christian P Schultz

10

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Roderick T Bronson

12

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25 March 2018

Denise Crowley

13

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Francis J Hornicek

16

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25 March 2018

language of work or name

English

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publication date

5 August 2007

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25 March 2018

published in

Nature Medicine

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25 March 2018

volume

13

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25 March 2018

page(s)

992-997

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25 March 2018

issue

8

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25 March 2018

https://scigraph.springernature.com/pub.10.1038/nm1602

exact match

0 references

cites work

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Bax suppresses tumorigenesis and stimulates apoptosis in vivo

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Mutational status of K-ras and TP53 genes in primary sarcomas of the heart

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Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

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Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

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Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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The INK4a/ARF network in tumour suppression

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

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The mitochondrion: is it central to apoptosis?

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Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice

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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

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Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease

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Tomographic fluorescence mapping of tumor targets

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7 January 2021

Identifiers

DOI

10.1038/NM1602

1 reference

25 March 2018

PubMed ID

17676052

1 reference

25 March 2018