(Q50958025)

English

Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia.

scientific article published on 27 May 2013

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

based on heuristic

inferred from title

T follicular helper cell

1 reference

based on heuristic

inferred from title

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Matthew J Ahearne

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Shaun Willimott

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Lucia Piñon

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

D Benjamin Kennedy

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Fiona Miall

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

0 references

publication date

27 May 2013

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

British Journal of Haematology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

162

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

360-370

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

High IL-21 receptor expression and apoptosis induction by IL-21 in follicular lymphoma

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Cd4+ T-cell immune response to large B-cell non-Hodgkin's lymphoma predicts patient outcome.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

The microenvironment in mature B-cell malignancies: a target for new treatment strategies

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Regulatory T-cell number is increased in chronic lymphocytic leukemia patients and correlates with progressive disease

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Selective elimination of a chemoresistant side population of B-CLL cells by cytotoxic T lymphocytes in subjects receiving an autologous hCD40L/IL-2 tumor vaccine

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

IL-21 mediates apoptosis through up-regulation of the BH3 family member BIM and enhances both direct and antibody-dependent cellular cytotoxicity in primary chronic lymphocytic leukemia cells in vitro

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

B-chronic lymphocytic leukemia chemoresistance involves innate and acquired leukemic side population cells

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

A distinct "side population" of cells with high drug efflux capacity in human tumor cells

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemia

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Ovarian cancer stem-like side-population cells are tumourigenic and chemoresistant

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Release of clonal block in B cell chronic lymphocytic leukaemia by engagement of co-operative epitopes on CD40.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

IL-4 biology: impact on normal and leukemic CLL B cells

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Follicular helper T cells are required for systemic autoimmunity

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Expansion of a CD8(+)PD-1(+) replicative senescence phenotype in early stage CLL patients is associated with inverted CD4:CD8 ratios and disease progression.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

A critical role for IL-21 in regulating immunoglobulin production

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Follicular lymphoma cell niche: identification of a preeminent IL-4-dependent T(FH)-B cell axis.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Cytokine-secreting follicular T cells shape the antibody repertoire

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

T-cell function in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Effective collaboration between IL-4 and IL-21 on B cell activation.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Interleukin 21 correlates with T cell and B cell subset alterations in systemic lupus erythematosus.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

A phase I dose-finding trial of recombinant interleukin-21 and rituximab in relapsed and refractory low grade B-cell lymphoproliferative disorders

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Interleukin-21 receptor (IL-21R) is up-regulated by CD40 triggering and mediates proapoptotic signals in chronic lymphocytic leukemia B cells

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

The opposite effects of IL-15 and IL-21 on CLL B cells correlate with differential activation of the JAK/STAT and ERK1/2 pathways

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

CD154 induces a switch in pro-survival Bcl-2 family members in chronic lymphocytic leukaemia.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Separate cell culture conditions to promote proliferation or quiescent cell survival in chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

1 reference

https://api.crossref.org/works/10.1111%2FBJH.12401

21 January 2018

Identifiers

10.1111/BJH.12401

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23710828%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q50958025&oldid=1625898939"