(Q50991697)

26 March 2018

title

A role for the immunological synapse in lineage commitment of CD4 lymphocytes. (English)

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26 March 2018

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4

Laurie H Glimcher

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26 March 2018

author name string

Roberto A Maldonado

series ordinal

1

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26 March 2018

Darrell J Irvine

series ordinal

2

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26 March 2018

Robert Schreiber

series ordinal

3

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26 March 2018

language of work or name

English

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publication date

22 September 2004

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26 March 2018

number of pages

6

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inferred from page(s)

published in

Nature

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26 March 2018

volume

431

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26 March 2018

issue

7008

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26 March 2018

page(s)

527-532

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26 March 2018

https://scigraph.springernature.com/pub.10.1038/nature02916

exact match

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cites work

T-cell-antigen recognition and the immunological synapse

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The immunological synapse: a molecular machine controlling T cell activation

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The immunological synapse.

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T lymphocyte costimulation mediated by reorganization of membrane microdomains

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Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells.

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A SLAT in the Th2 Signalosome

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Molecular mechanisms regulating Th1 immune responses

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Cytokines induce the development of functionally heterogeneous T helper cell subsets

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The lineage decisions of helper T cells

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7 January 2021

Two-photon imaging of lymphocyte motility and antigen response in intact lymph node

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7 January 2021

Cholesterol-dependent clustering of IL-2Ralpha and its colocalization with HLA and CD48 on T lymphoma cells suggest their functional association with lipid rafts.

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7 January 2021

Stat5 activation plays a critical role in Th2 differentiation

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7 January 2021

Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains

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Leishmania major infection of inbred mice: unmasking genetic determinants of infectious diseases

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Natural killer cell inhibitory receptors block actin cytoskeleton-dependent recruitment of 2B4 (CD244) to lipid rafts

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Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation

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7 January 2021

T cell receptor signaling precedes immunological synapse formation

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7 January 2021

Continuous T cell receptor signaling required for synapse maintenance and full effector potential

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The immunological synapse balances T cell receptor signaling and degradation

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Receptor-directed focusing of lymphokine release by helper T cells

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Delivering the kiss of death

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Cutting edge: in vivo identification of TCR redistribution and polarized IL-2 production by naive CD4 T cells

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Inducible IL-2 production by dendritic cells revealed by global gene expression analysis.

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STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation.

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Signaling via the T cell antigen receptor induces phosphorylation of Stat1 on serine 727

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Transient inhibition of interleukin 4 signaling by T cell receptor ligation

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Interferon gamma stabilizes the T helper cell type 1 phenotype.

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IL-4 Rapidly Produced by Vβ4 Vα8 CD4+ T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice

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Membrane raft microdomains in chemokine receptor function

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Lipid rafts in neuronal signaling and function.

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7 January 2021

Identifiers

DOI

10.1038/NATURE02916

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26 March 2018

Dimensions Publication ID

1021281222

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26 March 2018