(Q51017414)

http://europepmc.org/abstract/MED/21389242

27 March 2018

title

Interleukin-1alpha and HMGB1 mediate hippocampal dysfunction in SIGIRR-deficient mice. (English)

1 reference

http://europepmc.org/abstract/MED/21389242

27 March 2018

author

Derek A Costello

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

Marina A Lynch

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

Ciaran Murphy-Royal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

3

Thelma R Cowley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

author name string

Melanie B Watson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

Niamh Murphy

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

Cecilia Garlanda

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

language of work or name

English

0 references

publication date

1 March 2011

1 reference

http://europepmc.org/abstract/MED/21389242

27 March 2018

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

volume

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

page(s)

3871-3879

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

15 May 2020

cites work

1 reference

12 December 2020

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice.

1 reference

12 December 2020

Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily

1 reference

12 December 2020

HMG-1 as a late mediator of endotoxin lethality in mice

1 reference

12 December 2020

1 reference

12 December 2020

The inhibitory effects of interleukin-6 on synaptic plasticity in the rat hippocampus are associated with an inhibition of mitogen-activated protein kinase ERK

1 reference

12 December 2020

The inhibitory effect of interleukin-1beta on long-term potentiation is coupled with increased activity of stress-activated protein kinases

1 reference

12 December 2020

The pro-inflammatory cytokine interleukin-18 impairs long-term potentiation and NMDA receptor-mediated transmission in the rat hippocampus in vitro

1 reference

12 December 2020

Hippocampal A beta 42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice.

1 reference

12 December 2020

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

1 reference

12 December 2020

Memory for context is impaired by a post context exposure injection of interleukin-1 beta into dorsal hippocampus

1 reference

12 December 2020

Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1 beta on long term potentiation in rat dentate gyrus

1 reference

12 December 2020

Interleukin-1 receptor antagonist exerts agonist activity in the hippocampus independent of the interleukin-1 type I receptor

1 reference

12 December 2020

HMGB1 as a cytokine and therapeutic target

1 reference

12 December 2020

Activation of the c-Jun N-terminal kinase signaling cascade mediates the effect of amyloid-beta on long term potentiation and cell death in hippocampus: a role for interleukin-1beta?

1 reference

12 December 2020

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling

1 reference

12 December 2020

Tumor necrosis factor alters synaptic transmission in rat hippocampal slices

1 reference

12 December 2020

Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases

1 reference

12 December 2020

Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex

1 reference

12 December 2020

A dual role for interleukin-1 in LTP in mouse hippocampal slices

1 reference

12 December 2020

Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects

1 reference

12 December 2020

Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR.

1 reference

12 December 2020

Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family

1 reference

12 December 2020

The role of c-Jun N-terminal kinase in the A beta-mediated impairment of LTP and regulation of synaptic transmission in the hippocampus

1 reference

12 December 2020

Overexpression of type-1 adenylyl cyclase in mouse forebrain enhances recognition memory and LTP.

1 reference

12 December 2020

Forebrain degeneration and ventricle enlargement caused by double knockout of Alzheimer's presenilin-1 and presenilin-2

1 reference

12 December 2020

Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

1 reference

12 December 2020

The role of inflammation in Alzheimer's disease

1 reference

12 December 2020

The nitric oxide donor molsidomine antagonizes age-related memory deficits in the rat.

1 reference

12 December 2020

RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages

1 reference

12 December 2020

Activation of c-Jun-N-terminal kinase is critical in mediating lipopolysaccharide-induced changes in the rat hippocampus.

1 reference

12 December 2020

SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms

1 reference

12 December 2020

TLR signaling tailors innate immune responses in human microglia and astrocytes

1 reference

12 December 2020

High mobility group box 1 protein interacts with multiple Toll-like receptors

1 reference

12 December 2020

Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.

1 reference

12 December 2020

SIGIRR promotes resistance against Pseudomonas aeruginosa keratitis by down-regulating type-1 immunity and IL-1R1 and TLR4 signaling

1 reference

12 December 2020

Innate immune receptor expression in normal brain aging.

1 reference

12 December 2020

Different roles of TiR8/Sigirr on toll-like receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells.

1 reference

12 December 2020

Increased Susceptibility to Colitis-Associated Cancer of Mice Lacking TIR8, an Inhibitory Member of the Interleukin-1 Receptor Family

1 reference

12 December 2020

Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

1 reference

12 December 2020

Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.

1 reference

12 December 2020

Early release of HMGB-1 from neurons after the onset of brain ischemia

1 reference

12 December 2020

HMGB1 develops enhanced proinflammatory activity by binding to cytokines.

1 reference

12 December 2020

Age-dependent and -independent behavioral deficits in Tg2576 mice.

1 reference

12 December 2020

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

1 reference

12 December 2020

Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease

1 reference

12 December 2020

The effects of IL-1 receptor antagonist on beta amyloid mediated depression of LTP in the rat CA1 in vivo

1 reference

12 December 2020

TLR4 polymorphisms and ageing: implications for the pathophysiology of age-related diseases

1 reference

12 December 2020

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation.

1 reference

12 December 2020

Metaplastic regulation of long-term potentiation/long-term depression threshold by activity-dependent changes of NR2A/NR2B ratio.

1 reference

12 December 2020

Age-dependent impairment of spine morphology and synaptic plasticity in hippocampal CA1 neurons of a presenilin 1 transgenic mouse model of Alzheimer's disease.

1 reference

12 December 2020

TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization

1 reference

12 December 2020

Overexpression of type I adenylyl cyclase in the forebrain impairs spatial memory in aged but not young mice

1 reference

12 December 2020

Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice

1 reference

12 December 2020

Oral treatment with a gamma-secretase inhibitor improves long-term potentiation in a mouse model of Alzheimer's disease

1 reference

12 December 2020

The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation

1 reference

12 December 2020

Plastic modifications induced by object recognition memory processing

1 reference

12 December 2020

Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits

1 reference

12 December 2020

Mechanisms underlying inflammation in neurodegeneration

1 reference

12 December 2020

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

1 reference

12 December 2020

SIGIRR inhibits toll-like receptor 4, 5, 9-mediated immune responses in human airway epithelial cells

1 reference

12 December 2020

SIGIRR modulates the inflammatory response in the brain.

1 reference

12 December 2020

SIGIRR/TIR-8 is an inhibitor of toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis

1 reference

12 December 2020

Systemic administration of lipopolysaccharide induces molecular and morphological alterations in the hippocampus.

1 reference

12 December 2020

Toll-like receptor 3 inhibits memory retention and constrains adult hippocampal neurogenesis.

1 reference

12 December 2020

10.1523/JNEUROSCI.6676-10.2011

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6622806&resulttype=core&format=json

15 May 2020

1 reference