(Q51051082)

English

A Phase 1 study of the safety, pharmacokinetics and anti-leukemic activity of the anti-CD123 monoclonal antibody CSL360 in relapsed, refractory or high-risk acute myeloid leukemia.

scientific article published on 20 November 2014

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scholarly article

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25248882

A Phase 1 study of the safety, pharmacokinetics and anti-leukemic activity of the anti-CD123 monoclonal antibody CSL360 in relapsed, refractory or high-risk acute myeloid leukemia. (English)

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25248882

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based on heuristic

inferred from title

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based on heuristic

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pharmacokinetics

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based on heuristic

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Andrew J. McLachlan

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27 March 2018

http://europepmc.org/abstract/MED/25248882

14

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http://europepmc.org/abstract/MED/25248882

Andrew W. Roberts

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http://europepmc.org/abstract/MED/25248882

Hayley S. Ramshaw

object named as

Hayley S Ramshaw

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object named as

Ian Kerridge

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author name string

Simon Z He

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Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25248882

Samantha Busfield

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http://europepmc.org/abstract/MED/25248882

David S Ritchie

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http://europepmc.org/abstract/MED/25248882

Mark S Hertzberg

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http://europepmc.org/abstract/MED/25248882

Simon Durrant

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http://europepmc.org/abstract/MED/25248882

Ian D Lewis

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http://europepmc.org/abstract/MED/25248882

Paula Marlton

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http://europepmc.org/abstract/MED/25248882

Kenneth F Bradstock

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Glen Kennedy

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Andrew W Boyd

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http://europepmc.org/abstract/MED/25248882

Trina M Yeadon

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http://europepmc.org/abstract/MED/25248882

Harry Iland

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http://europepmc.org/abstract/MED/25248882

Simone Bamford

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http://europepmc.org/abstract/MED/25248882

Megan Barnden

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Mark DeWitte

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http://europepmc.org/abstract/MED/25248882

Russell Basser

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publication date

20 November 2014

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27 March 2018

http://europepmc.org/abstract/MED/25248882

Leukemia & Lymphoma

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56

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5

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1406-1415

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http://europepmc.org/abstract/MED/25248882

The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: ...

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

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Preferential induction of apoptosis for primary human leukemic stem cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

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Tumour stem cells and drug resistance

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

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The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Detection of molecular targets on the surface of CD34+/CD38-- stem cells in various myeloid malignancies.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Interleukin-3 receptor in acute leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

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Elevated expression of IL-3Ralpha in acute myelogenous leukemia is associated with enhanced blast proliferation, increased cellularity, and poor prognosis.

1 reference

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21 January 2018

Expression and prognostic value of hemopoietic cytokine receptors in acute myeloid leukemia (AML): implications for future therapeutical strategies

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

High levels of CD34+CD38low/-CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucemies Aigues et Maladies du Sang (GOELAMS) study.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Antibody pharmacokinetics and pharmacodynamics

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https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Right on target: eradicating leukemic stem cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Recent advances in acute myeloid leukemia stem cell biology

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

C-type lectin-like molecule-1: a novel myeloid cell surface marker associated with acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Complete remissions observed in acute myeloid leukemia following prolonged exposure to lintuzumab: a phase 1 trial

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

New immunotoxins targeting CD123, a stem cell antigen on acute myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Targeting of acute myeloid leukaemia by cytokine-induced killer cells redirected with a novel CD123-specific chimeric antigen receptor.

1 reference

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21 January 2018

T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor-modified T cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Targeting of acute myeloid leukemia in vitro and in vivo with an anti-CD123 mAb engineered for optimal ADCC.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2014.956316

21 January 2018

Identifiers

10.3109/10428194.2014.956316

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25248882

1 reference

Europe PubMed Central

27 March 2018

http://europepmc.org/abstract/MED/25248882

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