(Q34283145)

1 August 2017

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title

Interleukin-3 receptor in acute leukemia (English)

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1 August 2017

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Testa U

1

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1 August 2017

Riccioni R

2

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1 August 2017

Diverio D

3

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1 August 2017

Rossini A

4

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1 August 2017

Lo Coco F

5

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1 August 2017

Peschle C

6

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1 August 2017

1 February 2004

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1 August 2017

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1 August 2017

18

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1 August 2017

2

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1 August 2017

219-226

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2403224

1 August 2017

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PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model

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AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

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Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

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Chromosome translocations and covert leukemic clones are generated during normal fetal development

21 January 2018

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Origins of chromosome translocations in childhood leukaemia

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The roles of FLT3 in hematopoiesis and leukemia

21 January 2018

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Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.

21 January 2018

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Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification

21 January 2018

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Elevated expression of IL-3Ralpha in acute myelogenous leukemia is associated with enhanced blast proliferation, increased cellularity, and poor prognosis.

21 January 2018

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Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs

21 January 2018

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Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors

21 January 2018

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Identification of primary structural features that define the differential actions of IL-3 and GM-CSF receptors

21 January 2018

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Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway.

21 January 2018

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The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kappaB and induction of bcl-2.

21 January 2018

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Phosphatidylinositol 3-kinase is essential for kit ligand-mediated survival, whereas interleukin-3 and flt3 ligand induce expression of antiapoptotic Bcl-2 family genes

21 January 2018

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The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor

21 January 2018

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The pims and outs of survival signaling: role for the Pim-2 protein kinase in the suppression of apoptosis by cytokines

21 January 2018

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Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling

21 January 2018

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The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia

21 January 2018

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Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.

21 January 2018

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Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

21 January 2018

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Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells.

21 January 2018

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Sequential mutations in the interleukin-3 (IL3)/granulocyte-macrophage colony-stimulating factor/IL5 receptor beta-subunit genes are necessary for the complete conversion to growth autonomy mediated by a truncated beta C subunit

21 January 2018

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Mice deficient for the IL-3/GM-CSF/IL-5 beta c receptor exhibit lung pathology and impaired immune response, while beta IL3 receptor-deficient mice are normal

21 January 2018

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Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5.

21 January 2018

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Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression

21 January 2018

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PU.1 regulation of human alveolar macrophage differentiation requires granulocyte-macrophage colony-stimulating factor

21 January 2018

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The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

21 January 2018

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Preferential induction of apoptosis for primary human leukemic stem cells

21 January 2018

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A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 January 2018

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The coupling of TEL/PDGFbetaR to distinct functional responses is modulated by the presence of cytokine: involvement of mitogen-activated protein kinases.

21 January 2018

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The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells.

21 January 2018

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Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells

21 January 2018

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The role of FLT3 in haematopoietic malignancies

21 January 2018

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FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy

21 January 2018

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Selective cytotoxic mechanism of GTP-14564, a novel tyrosine kinase inhibitor in leukemia cells expressing a constitutively active Fms-like tyrosine kinase 3 (FLT3).

21 January 2018

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Different antiapoptotic pathways between wild-type and mutated FLT3: insights into therapeutic targets in leukemia

21 January 2018

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Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations

21 January 2018

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Comprehensive genotypic analysis of leukemia: clinical and therapeutic implications

21 January 2018

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FLT3: ITDoes matter in leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

Primitive interleukin 3 null hematopoietic cells transduced with BCR-ABL show accelerated loss after culture of factor-independence in vitro and leukemogenic activity in vivo.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML).

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

Diphtheria toxin-interleukin-3 fusion protein (DT(388)IL3) prolongs disease-free survival of leukemic immunocompromised mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

Expression of interleukin 3 and granulocyte-macrophage colony-stimulating factor receptor common chain betac, betaIT in normal haematopoiesis: lineage specificity and proliferation-independent induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

7 January 2021

Primitive quiescent leukemic cells from patients with chronic myeloid leukemia spontaneously initiate factor-independent growth in vitro in association with up-regulation of expression of interleukin-3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

7 January 2021

Relations between IL-3-induced proliferation and in vitro cytokine secretion of bone marrow cells from AML patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

7 January 2021

FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

7 January 2021

Targeting myeloid leukemia with a DT(390)-mIL-3 fusion immunotoxin: ex vivo and in vivo studies in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

7 January 2021

Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403224

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2403224

1 reference

Dimensions Publication ID

1 August 2017

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