(Q51066803)

28 March 2018

title

Human uridine phosphorylase-1 inhibitors: a new approach to ameliorate 5-fluorouracil-induced intestinal mucositis. (English)

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28 March 2018

author

Maria Martha Campos

7

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28 March 2018

Luiz A. Basso

8

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28 March 2018

Pablo Machado

object named as

Pablo Machado

3

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author name string

Daiana Renck

1

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28 March 2018

André A Santos

2

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28 March 2018

Guilherme O Petersen

4

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28 March 2018

Tiago G Lopes

5

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28 March 2018

Diógenes S Santos

6

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28 March 2018

publication date

23 July 2014

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28 March 2018

Investigational New Drugs

published in

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28 March 2018

volume

32

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28 March 2018

issue

6

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28 March 2018

page(s)

1301-1307

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28 March 2018

https://scigraph.springernature.com/pub.10.1007/s10637-014-0135-0

exact match

0 references

cites work

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1 reference

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5-Fluorouracil: forty-plus and still ticking. A review of its preclinical and clinical development

21 January 2018

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Gastrointestinal dysmotility in 5-fluorouracil-induced intestinal mucositis outlasts inflammatory process resolution

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10637-014-0135-0

Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis

21 January 2018

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New thoughts on the initiation of mucositis

21 January 2018

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The pathobiology of mucositis

21 January 2018

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Minocycline attenuates 5-fluorouracil-induced small intestinal mucositis in mouse model

21 January 2018

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Mucositis: The impact, biology and therapeutic opportunities of oral mucositis

21 January 2018

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Animal models of mucositis: implications for therapy.

21 January 2018

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Updated clinical practice guidelines for the prevention and treatment of mucositis

21 January 2018

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Intestinal permeability in patients with chemotherapy-induced stomatitis.

21 January 2018

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Modulation of 5-fluorouracil host-toxicity and chemotherapeutic efficacy against human colon tumors by 5-(Phenylthio)acyclouridine, a uridine phosphorylase inhibitor

21 January 2018

1 reference

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Design of novel potent inhibitors of human uridine phosphorylase-1: synthesis, inhibition studies, thermodynamics, and in vitro influence on 5-fluorouracil cytotoxicity.

21 January 2018

1 reference

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Potent combination therapy for human breast tumors with high doses of 5-fluorouracil: remission and lack of host toxicity

21 January 2018

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Effects of acid antisecretory drugs on mucus barrier of the rat against 5-fluorouracil-induced gastrointestinal mucositis

21 January 2018

1 reference

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Role of platelet-activating factor in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice.

21 January 2018

1 reference

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Pre-treatment with insulin-like growth factor-I partially ameliorates 5-fluorouracil-induced intestinal mucositis in rats

21 January 2018

1 reference

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Modulation of fluorouracil toxicity with uridine

21 January 2018

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12 December 2020

Phase I and pharmacokinetic studies of high-dose uridine intended for rescue from 5-fluorouracil toxicity

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12 December 2020

Species-dependent differences in the biochemical effects and metabolism of 5-benzylacyclouridine

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12 December 2020

Pyrimidine acyclonucleosides, inhibitors of uridine phosphorylase

1 reference

12 December 2020

10.1007/S10637-014-0135-0

Identifiers

DOI

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28 March 2018

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28 March 2018