(Q51069064)

28 March 2018

title

Epigenetic regulation of canonical TNFα pathway by HDAC1 determines survival of cardiac myocytes. (English)

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28 March 2018

author name string

Hongying Gang

1

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28 March 2018

James Shaw

2

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28 March 2018

Rimpy Dhingra

3

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28 March 2018

James R Davie

4

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28 March 2018

Lorrie A Kirshenbaum

5

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28 March 2018

publication date

12 April 2013

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28 March 2018

American Journal of Physiology Heart and Circulatory Physiology

published in

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28 March 2018

volume

304

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issue

12

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28 March 2018

page(s)

H1662-9

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28 March 2018

The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression

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1 reference

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

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Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

21 January 2018

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Basal phosphorylation of the PEST domain in the I(kappa)B(beta) regulates its functional interaction with the c-rel proto-oncogene product

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NF-κB and IκBα Are Found in the Mitochondria

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Histone deacetylases (HDACs): characterization of the classical HDAC family

21 January 2018

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Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions

21 January 2018

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A role for histone deacetylase activity in HDAC1-mediated transcriptional repression

21 January 2018

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How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

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Adenovirus E1A represses cardiac gene transcription and reactivates DNA synthesis in ventricular myocytes, via alternative pocket protein- and p300-binding domains.

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Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction

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Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

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Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

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Control of muscle development by dueling HATs and HDACs

21 January 2018

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Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation

21 January 2018

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Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors

21 January 2018

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p53 activates the mitochondrial death pathway and apoptosis of ventricular myocytes independent of de novo gene transcription

21 January 2018

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21 January 2018

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Transcriptional silencing of the death gene BNIP3 by cooperative action of NF-kappaB and histone deacetylase 1 in ventricular myocytes

21 January 2018

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Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

21 January 2018

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

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10.1152/AJPHEART.00093.2013

21 January 2018

Identifiers

DOI

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28 March 2018

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28 March 2018