(Q51081157)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24903407%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Complex disruption effect of natural polyphenols on Bcl-2-Bax: molecular dynamics simulation and essential dynamics study (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24903407%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24903407%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

author name string

Amit Singh

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24903407%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Abha Mishra

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24903407%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

publication date

14 July 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24903407%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomolecular Structure and Dynamics

20 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24903407%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24903407%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24903407%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

page(s)

1094-1106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24903407%20AND%20SRC:MED&resulttype=core&format=json

Life-or-death decisions by the Bcl-2 protein family.

20 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

GROMACS: A message-passing parallel molecular dynamics implementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Bcl-2 and Bax interact via the BH1-3 groove-BH3 motif interface and a novel interface involving the BH4 motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Bcl-2 changes conformation to inhibit Bax oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

The pathophysiology of mitochondrial cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Molecular interactions of prodiginines with the BH3 domain of anti-apoptotic Bcl-2 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

The chemopreventive effect of taxifolin is exerted through ARE-dependent gene regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

The structure of a Bcl-xL/Bim fragment complex: implications for Bim function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Dynamics of Bcl-xL in water and membrane: molecular simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Novel 9-(alkylthio)-Acenaphtho[1,2-e]-1,2,4-triazine derivatives: synthesis, cytotoxic activity and molecular docking studies on B-cell lymphoma 2 (Bcl-2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Apoptosis in the development and maintenance of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Solution structure of the antiapoptotic protein bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Structural biology of the Bcl-2 family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Molecular dynamics study of peptide segments of the BH3 domain of the proapoptotic proteins Bak, Bax, Bid and Hrk bound to the Bcl-xL and Bcl-2 proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Molecular dynamics simulations of the Bcl-2 protein to predict the structure of its unordered flexible loop domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Molecular interactions of Bcl-2 and Bcl-xL with mortalin: identification and functional characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Preventive effect of the flavonoid, quercetin, on hepatic cancer in rats via oxidant/antioxidant activity: molecular and histological evidences

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Structure of Bax: coregulation of dimer formation and intracellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Acylpyrogallols as inhibitors of antiapoptotic Bcl-2 proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

The distal pathway of lipoprotein-induced cholesterol esterification, but not sphingomyelinase-induced cholesterol esterification, is energy-dependent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based upon a New Scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

GROMACS 3.0: a package for molecular simulation and trajectory analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2014.931823

10.1080/07391102.2014.931823

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24903407%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference