(Q37232056)

19 August 2017

Molecular interactions of Bcl-2 and Bcl-xL with mortalin: identification and functional characterization (English)

1 reference

19 August 2017

molecular interaction

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24050266%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Ran Gao

5

1 reference

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14 June 2020

Sunil C Kaul

7

1 reference

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14 June 2020

Renu Wadhwa

8

1 reference

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14 June 2020

4

Abhinav Grover

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24050266%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

6

Durai Sundar

1 reference

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14 June 2020

author name string

Nishant Saxena

1

1 reference

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14 June 2020

Ye Liu

3

1 reference

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14 June 2020

publication date

16 October 2013

1 reference

19 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24050266%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24050266%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24050266%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

14 June 2020

copyright license

start time

25 July 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy

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Selective killing of cancer cells by leaf extract of Ashwagandha: identification of a tumor-inhibitory factor and the first molecular insights to its effect

9 September 2017

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Bcl2's flexible loop domain regulates p53 binding and survival

9 September 2017

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Mortalin-based cytoplasmic sequestration of p53 in a nonmammalian cancer model

9 September 2017

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BCL2 family of apoptosis-related genes: functions and clinical implications in cancer

9 September 2017

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Unknotting the roles of Bcl-2 and Bcl-xL in cell death

9 September 2017

1 reference

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Structural biology of the Bcl-2 family of proteins

9 September 2017

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Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.

9 September 2017

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Modeller: generation and refinement of homology-based protein structure models

9 September 2017

1 reference

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Mono- and multisite phosphorylation enhances Bcl2's antiapoptotic function and inhibition of cell cycle entry functions

9 September 2017

1 reference

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Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

HADDOCK: a protein-protein docking approach based on biochemical or biophysical information

9 September 2017

1 reference

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Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75.

9 September 2017

1 reference

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Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein

9 September 2017

1 reference

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Bcl-2 family proteins as targets for anticancer drug design

9 September 2017

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Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2

9 September 2017

1 reference

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Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes

9 September 2017

1 reference

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Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries

9 September 2017

1 reference

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VMD: visual molecular dynamics

9 September 2017

1 reference

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Diminished cell proliferation associated with the death-protective activity of Bcl-2

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death

9 September 2017

1 reference

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Induction of mutant p53-dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin.

9 September 2017

1 reference

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Mortalin overexpression attenuates beta-amyloid-induced neurotoxicity in SH-SY5Y cells.

14 September 2017

1 reference

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Stress chaperones, mortalin, and pex19p mediate 5-aza-2' deoxycytidine-induced senescence of cancer cells by DNA methylation-independent pathway.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Activation of wild type p53 function by its mortalin-binding, cytoplasmically localizing carboxyl terminus peptides.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Reduction in mortalin level by its antisense expression causes senescence-like growth arrest in human immortalized cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Bcl-xL and E1B-19K proteins inhibit p53-induced irreversible growth arrest and senescence by preventing reactive oxygen species-dependent p38 activation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Life span shortening of normal fibroblasts by overexpression of BCL-2: a result of potent increase in cell death

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Malignant transformation of NIH3T3 cells by overexpression of mot-2 protein.

28 September 2017

1 reference

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Decrease in amplified telomeric sequences and induction of senescence markers by introduction of human chromosome 7 or its segments in SUSM-1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Overexpression of mitochondrial Hsp70/Hsp75 in rat brain protects mitochondria, reduces oxidative stress, and protects from focal ischemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

InterProSurf: a web server for predicting interacting sites on protein surfaces

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Mortalin controls centrosome duplication via modulating centrosomal localization of p53.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Effect of GRP75/mthsp70/PBP74/mortalin overexpression on intracellular ATP level, mitochondrial membrane potential and ROS accumulation following glucose deprivation in PC12 cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Detection of mitochondrial localization of p53.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Expression level of Bcl-2 determines anti- or proapoptotic function.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Bcl-2 slows in vitro breast cancer growth despite its antiapoptotic effect

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3797589

Withanone binds to mortalin and abrogates mortalin–p53 complex: Computational and experimental evidence

3 September 2018

1 reference

12 December 2020

Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts

1 reference

12 December 2020

Prognostic significance of Bcl-xL in human hepatocellular carcinoma

1 reference

12 December 2020

Mitochondrial stress protein actions during chemically induced renal proximal tubule cell death

1 reference

12 December 2020

Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival

1 reference

12 December 2020

ProtorP: a protein-protein interaction analysis server

1 reference

12 December 2020

Identifiers

DOI

10.1042/BSR20130034

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24050266%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24050266%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

PubMed publication ID

24050266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24050266%20AND%20SRC:MED&resulttype=core&format=json