(Q51097493)

29 March 2018

review article

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title

Receptor editing and commitment in B lymphocytes. (English)

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29 March 2018

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M Hertz

1

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29 March 2018

D Nemazee

series ordinal

2

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29 March 2018

publication date

1 April 1998

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29 March 2018

Current Opinion in Immunology

published in

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29 March 2018

volume

10

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29 March 2018

issue

2

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29 March 2018

page(s)

208-213

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29 March 2018

Most peripheral B cells in mice are ligand selected

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Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death.

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Receptor editing, immune diversification, and self-tolerance

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Editing disease-associated autoantibodies

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Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

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Changes in locus-specific V(D)J recombinase activity induced by immunoglobulin gene products during B cell development

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BCR ligation induces receptor editing in IgM+IgD- bone marrow B cells in vitro

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Self-antigen does not accelerate immature B cell apoptosis, but stimulates receptor editing as a consequence of developmental arrest.

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7 January 2021

Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells

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7 January 2021

Transitional B cells are the target of negative selection in the B cell compartment

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B-lineage differentiation stages resolved by multiparameter flow cytometry

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Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires

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Influences on the lifespan of B cell subpopulations defined by different phenotypes.

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Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

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MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

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7 January 2021

Initiation and processing of signals from the B cell antigen receptor

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The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity

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Requirement for invariant chain in B cell maturation and function.

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Molecular mechanisms in B cell antigen receptor signaling

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Regulation of antigen receptor signal transduction by protein tyrosine kinases

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The motheaten mutation rescues B cell signaling and development in CD45-deficient mice

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The "clonal selection hypothesis" and current concepts of B cell tolerance

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Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.

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Outer periarteriolar lymphoid sheath arrest and subsequent differentiation of both naive and tolerant immunoglobulin transgenic B cells is determined by B cell receptor occupancy

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Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate

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Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: localization to the T-B interface of the splenic follicle

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Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor.

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Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells.

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CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells

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Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions

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Soluble antigen can cause enhanced apoptosis of germinal-centre B cells.

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Antigen-induced B-cell death and elimination during germinal-centre immune responses

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7 January 2021

Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells

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7 January 2021

Reexpression of RAG-1 and RAG-2 genes in activated mature mouse B cells

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7 January 2021

V(D)J Recombination in Mature B Cells: A Mechanism for Altering Antibody Responses

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7 January 2021

V(D)J recombinase activity in a subset of germinal center B lymphocytes

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7 January 2021

B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen.

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7 January 2021

Peripheral deletion of self-reactive B cells

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7 January 2021

kappa+lambda+ dual receptor B cells are present in the human peripheral repertoire

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7 January 2021

Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980250-1

7 January 2021

10.1016/S0952-7915(98)80250-1

Identifiers

DOI

1 reference

29 March 2018

1 reference

29 March 2018