(Q51128609)

30 March 2018

title

Baffled by bafilomycin: an anticancer agent that induces hypoxia-inducible factor-1alpha expression. (English)

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30 March 2018

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1

Gregg L Semenza

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30 March 2018

publication date

25 September 2006

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30 March 2018

published in

Molecular Pharmacology

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30 March 2018

volume

70

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30 March 2018

issue

6

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30 March 2018

page(s)

1841-1843

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30 March 2018

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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Hypoxia, clonal selection, and the role of HIF-1 in tumor progression

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Inhibiting hypoxia-inducible factor 1 for cancer therapy

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HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron

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A model for the proteolipid ring and bafilomycin/concanamycin-binding site in the vacuolar ATPase of Neurospora crassa

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Bafilomycin induces the p21-mediated growth inhibition of cancer cells under hypoxic conditions by expressing hypoxia-inducible factor-1alpha.

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Cancer genes and the pathways they control

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Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B.

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

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https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.106.031062

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

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Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways

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Purification and characterization of hypoxia-inducible factor 1

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Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

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https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.106.031062

HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression.

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.106.031062

Regulation of angiogenesis by hypoxia-inducible factor 1.

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.106.031062

Aberrant gene silencing in tumor progression: implications for control of cancer

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.106.031062

Identifiers

DOI

10.1124/MOL.106.031062

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30 March 2018

1 reference

30 March 2018