(Q47985714)

7 February 2018

title

Proceedings of the Oxygen Homeostasis/Hypoxia Meeting (English)

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7 February 2018

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8

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7 February 2018

Adrian Harris

10

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7 February 2018

Randall S. Johnson

12

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7 February 2018

Patrick H. Maxwell

15

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7 February 2018

Erik Storkebaum

object named as

Erik Storkebaum

22

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Gregg L. Semenza

20

object named as

Gregg L Semenza

1 reference

7 February 2018

13

William Kaelin

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7 February 2018

18

Garth Powis

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7 February 2018

17

Len Neckers

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7 February 2018

author name string

Bennett Kaufman

1

1 reference

7 February 2018

Orit Scharf

2

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7 February 2018

Jeffrey Arbeit

3

1 reference

7 February 2018

Margaret Ashcroft

4

1 reference

7 February 2018

J Martin Brown

5

1 reference

7 February 2018

Richard K Bruick

6

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7 February 2018

J Donald Chapman

7

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7 February 2018

Amato J Giaccia

9

1 reference

7 February 2018

Eric Huang

11

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7 February 2018

Cameron J Koch

14

1 reference

7 February 2018

James Mitchell

16

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7 February 2018

Joseph Rajendran

19

1 reference

7 February 2018

Jonathan Simons

21

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7 February 2018

Michael J Welch

23

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7 February 2018

Murray Whitelaw

24

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7 February 2018

Giovanni Melillo

25

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7 February 2018

S Percy Ivy

26

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7 February 2018

language of work or name

English

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publication date

1 May 2004

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7 February 2018

published in

Cancer Research

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7 February 2018

volume

64

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7 February 2018

issue

9

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7 February 2018

page(s)

3350-3356

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7 February 2018

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

cites work

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/20459

Non-invasive PET and SPECT imaging of tissue hypoxia using isotopically labeled 2-nitroimidazoles.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Hypoxia-inducible factor and its biomedical relevance

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Physiology meets biophysics: visualizing the interaction of hypoxia-inducible factor 1 alpha with p300 and CBP

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Hypoxia in human prostate carcinoma: an Eppendorf PO2 study.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Targeting HIF-1 for cancer therapy

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

High purity production and potential applications of copper-60 and copper-61

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Treatment resistance of solid tumors: role of hypoxia and anemia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Hypoxia-inducible factor 1 regulates vascular endothelial growth factor expression in human pancreatic cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Hypoxia--a key regulatory factor in tumour growth

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Current status of knowledge and critical issues in tumor oxygenation. Results from 25 years research in tumor pathophysiology

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Hsp90: a specialized but essential protein-folding tool

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

The role of the redox protein thioredoxin in cell growth and cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

EPR imaging of vascular changes in oxygen in response to carbogen breathing.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Impact of tumor hypoxia and anemia on radiation therapy outcomes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Oxygen and the inflammatory cell

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

HIF-1alpha is essential for myeloid cell-mediated inflammation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Application of high-throughput, molecular-targeted screening to anticancer drug discovery

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Signal transduction to hypoxia-inducible factor 1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Noninvasive imaging of tumor hypoxia in rats using the 2-nitroimidazole 18F-EF5

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Structure-activity relationships of 1,2,4-benzotriazine 1,4-dioxides as hypoxia-selective analogues of tirapazamine

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Hypoxia links ATR and p53 through replication arrest

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Pancreatic tumors show high levels of hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Nuclear expression of hypoxia-inducible factor 1alpha protein is heterogeneous in human malignant cells under normoxic conditions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

The hypoxic core: a possible answer to the cancer paradox

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Heat-shock protein 90 inhibitors as novel cancer chemotherapeutic agents

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide].

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)a cet amide] : analysis of drug adducts by fluorescent antibodies vs bound radioactivity

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Hypoxic heterogeneity in human tumors: EF5 binding, vasculature, necrosis, and proliferation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Pharmacokinetics of EF5 [2-(2-nitro-1-H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide] in human patients: implications for hypoxia measurements in vivo by 2-nitroimidazoles.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Tumor hypoxia is important in radiotherapy, but how should we measure it?

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Hypoxic prostate/muscle pO2 ratio predicts for biochemical failure in patients with prostate cancer: preliminary findings.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

HIF-1 and tumor progression: pathophysiology and therapeutics

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-03-2611

Identifiers

DOI

10.1158/0008-5472.CAN-03-2611

1 reference

7 February 2018

1 reference

7 February 2018