(Q51204003)

http://europepmc.org/abstract/PMC/5336152

1 April 2018

title

Residues in the RecQ C-terminal Domain of the Human Werner Syndrome Helicase Are Involved in Unwinding G-quadruplex DNA. (English)

1 reference

http://europepmc.org/abstract/PMC/5336152

1 April 2018

1 reference

1 reference

G-quadruplex DNA

3 January 2024

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28069813%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Amit Ketkar

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28069813%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Markus Voehler

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28069813%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Robert L Eoff

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28069813%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

9 January 2017

1 reference

http://europepmc.org/abstract/PMC/5336152

1 April 2018

published in

Journal of Biological Chemistry

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28069813%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

292

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28069813%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28069813%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

3154-3163

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28069813%20AND%20SRC:MED&resulttype=core&format=json

Single-molecule imaging reveals a common mechanism shared by G-quadruplex-resolving helicases

9 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

G-quadruplex recognition and remodeling by the FANCJ helicase

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

The Werner syndrome RECQ helicase targets G4 DNA in human cells to modulate transcription.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

G-quadruplexes and helicases

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide-quadruplex complex

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Human RecQ helicases in DNA repair, recombination, and replication.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Folding and unfolding pathways of the human telomeric G-quadruplex

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Human Rev1 polymerase disrupts G-quadruplex DNA.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Overview: what are helicases?

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Solution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Helicase-catalysed translocation and strand separation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Modulation of Werner syndrome protein function by a single mutation in the conserved RecQ domain

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Gene expression profiling in Werner syndrome closely resembles that of normal aging

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Helicase mechanisms and the coupling of helicases within macromolecular machines. Part I: Structures and properties of isolated helicases

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Helicase structure and mechanism

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Werner syndrome protein: biochemical properties and functional interactions

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

The Werner syndrome protein is a DNA helicase

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Mutator phenotype of Werner syndrome is characterized by extensive deletions

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

A conserved G4 DNA binding domain in RecQ family helicases.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336152

Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28069813

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28069813

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genetic instability and hematologic disease risk in Werner syndrome patients and heterozygotes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28069813

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M116.767699

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28069813%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28069813%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference