(Q51306717)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

title

Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

0 references

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Björn Rissiek

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Eric Boué-Grabot

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

author name string

Welbeck Danquah

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Catherine Meyer-Schwesinger

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Carolina Pinto

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Arnau Serracant-Prat

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Miriam Amadi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Domenica Iacenda

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Jan-Hendrik Knop

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Anna Hammel

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Philine Bergmann

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Nicole Schwarz

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Joana Assunção

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Wendy Rotthier

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Friedrich Haag

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Eva Tolosa

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Peter Bannas

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Tim Magnus

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Toon Laeremans

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Catelijne Stortelers

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

language of work or name

English

0 references

publication date

1 November 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

Science Translational Medicine

28 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

issue

366

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

page(s)

366ra162

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

Increased expression of the pro-apoptotic ATP-sensitive P2X7 receptor in experimental and human glomerulonephritis.

28 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Gain-of-function of P2X7 receptor gene variants in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

P2X7 deficiency attenuates renal injury in experimental glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Lack of the purinergic receptor P2X(7) results in resistance to contact hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

The P2X7 receptor: a key player in IL-1 processing and release

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Nucleotide signalling during inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

NAD+ and ATP released from injured cells induce P2X7-dependent shedding of CD62L and externalization of phosphatidylserine by murine T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Antagonists of the P2X(7) receptor. From lead identification to drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Selective P2X(7) receptor antagonists for chronic inflammation and pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

P2X7 antagonists as potential therapeutic agents for the treatment of CNS disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

The microglial ATP-gated ion channel P2X7 as a CNS drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Clinical evaluation of the efficacy of the P2X7purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Efficacy and safety of CE-224,535, an antagonist of P2X7 receptor, in treatment of patients with rheumatoid arthritis inadequately controlled by methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Antibody therapeutics targeting ion channels: are we there yet?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Single domain antibodies: promising experimental and therapeutic tools in infection and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Nanobodies: natural single-domain antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular Nanobody technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

A novel platform for engineering blood-brain barrier-crossing bispecific biologics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Monitoring the expression of purinoceptors and nucleotide-metabolizing ecto-enzymes with antibodies directed against proteins in native conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

The preclinical pharmacology of the high affinity anti-IL-6R Nanobody® ALX-0061 supports its clinical development in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

P2X receptors as cell-surface ATP sensors in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Positive allosteric modulation by ivermectin of human but not murine P2X7 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Genetics of the P2X7 receptor and human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Caplacizumab for Acquired Thrombotic Thrombocytopenic Purpura

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Transient expression and purification of chimeric heavy chain antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Single domain antibodies from llama effectively and specifically block T cell ecto-ADP-ribosyltransferase ART2.2 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

Technical Advance: a new cell preparation strategy that greatly improves the yield of vital and functional Tregs and NKT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

A novel flow cytometric method to assess inflammasome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAF8463

10.1126/SCITRANSLMED.AAF8463

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27881823%20AND%20SRC:MED&resulttype=core&format=json

release_e2uxvtwcrvai3dbtk2634jehdq

28 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/e2uxvtwcrvai3dbtk2634jehdq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference