(Q51326513)

3 April 2018

title

Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production. (English)

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3 April 2018

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7

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3 April 2018

Aaron J. Marshall

8

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3 April 2018

Stephan Wullschleger

3

object named as

Stephan Wullschleger

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3 April 2018

author name string

Ivan Landego

1

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3 April 2018

Nipun Jayachandran

2

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3 April 2018

Ting-ting Zhang

4

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3 April 2018

Ian W Gibson

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3 April 2018

Angela Miller

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3 April 2018

language of work or name

English

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publication date

8 August 2012

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3 April 2018

European Journal of Immunology

published in

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3 April 2018

volume

42

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3 April 2018

issue

10

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3 April 2018

page(s)

2760-2770

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3 April 2018

Two distinct waves of membrane-proximal B cell antigen receptor signaling differentially regulated by Src homology 2-containing inositol polyphosphate 5-phosphatase

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Signal-dependent membrane targeting by pleckstrin homology (PH) domains

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Signalling through the lipid products of phosphoinositide-3-OH kinase

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Phosphoinositide 3-kinase-regulated adapters in lymphocyte activation.

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Impaired Fas response and autoimmunity in Pten+/- mice

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The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

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Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach

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Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

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PI3 kinase signals BCR-dependent mature B cell survival

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

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The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase

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Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

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7 January 2021

Phosphoinositide recognition domains

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High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

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7 January 2021

Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockou

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7 January 2021

The dynamics of protein kinase B regulation during B cell antigen receptor engagement

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7 January 2021

Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities

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7 January 2021

TAPP1 and TAPP2 are targets of phosphatidylinositol 3-kinase signaling in B cells: sustained plasma membrane recruitment triggered by the B-cell antigen receptor

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7 January 2021

Regulation of phosphoinositide 3-kinase signaling by oxidants: hydrogen peroxide selectively enhances immunoreceptor-induced recruitment of phosphatidylinositol (3,4) bisphosphate-binding PH domain proteins

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7 January 2021

Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo

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7 January 2021

Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificity

1 reference

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7 January 2021

Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis

1 reference

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7 January 2021

Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function

1 reference

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7 January 2021

PI(3,4,5)P3 and PI(3,4)P2 levels correlate with PKB/akt phosphorylation at Thr308 and Ser473, respectively; PI(3,4)P2 levels determine PKB activity.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242371

7 January 2021

The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.

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7 January 2021

Phosphoinositide 3-kinase p110 delta regulates natural antibody production, marginal zone and B-1 B cell function, and autoantibody responses

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7 January 2021

Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1

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7 January 2021

Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice

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7 January 2021

Differential regulation of B cell development, activation, and death by the src homology 2 domain-containing 5' inositol phosphatase (SHIP)

1 reference

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7 January 2021

The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling

1 reference

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7 January 2021

Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242371

7 January 2021

A differential requirement for phosphoinositide 3-kinase reveals two pathways for inducible upregulation of major histocompatibility complex class II molecules and CD86 expression by murine B lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242371

7 January 2021

Sex differences in autoimmune disease

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7 January 2021

Peripheral B cell receptor editing may promote the production of high-affinity autoantibodies in CD22-deficient mice.

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7 January 2021

Beneficial effects of the anti-oestrogen tamoxifen on systemic lupus erythematosus of (NZBxNZW)F1 female mice are associated with specific reduction of IgG3 autoantibodies

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242371

7 January 2021

Tamoxifen decreases renal inflammation and alleviates disease severity in autoimmune NZB/W F1 mice

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7 January 2021

Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection

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7 January 2021

Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242371

7 January 2021

Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242371

7 January 2021

A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242371

7 January 2021

Bam32/DAPP1 promotes B cell adhesion and formation of polarized conjugates with T cells.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242371

7 January 2021

Identifiers

DOI

10.1002/EJI.201242371

1 reference

3 April 2018

1 reference

3 April 2018