(Q51540804)

6 April 2018

title

Effects of UDP-glucuronosyltransferase polymorphisms on the pharmacokinetics of ezetimibe in healthy subjects. (English)

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6 April 2018

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Jung-Woo Bae

1

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6 April 2018

Chang-Ik Choi

2

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6 April 2018

Jin-Hee Lee

3

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6 April 2018

Choon-Gon Jang

4

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6 April 2018

Myeon-Woo Chung

5

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6 April 2018

Seok-Yong Lee

6

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6 April 2018

publication date

24 September 2010

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6 April 2018

European Journal of Clinical Pharmacology

published in

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6 April 2018

volume

67

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6 April 2018

issue

1

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6 April 2018

page(s)

39-45

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6 April 2018

https://scigraph.springernature.com/pub.10.1007/s00228-010-0899-x

exact match

0 references

cites work

Disposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjects

1 reference

12 December 2020

UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer

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12 December 2020

Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer

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12 December 2020

Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates.

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12 December 2020

Pharmacology and therapeutics of ezetimibe (SCH 58235), a cholesterol-absorption inhibitor

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12 December 2020

Two linked polymorphic mutations (A(TA)7TAA and T-3279G) of UGT1A1 as the principal cause of Gilbert syndrome

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12 December 2020

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

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12 December 2020

Distribution of the UGT1A1*28 polymorphism in Caucasian and Asian populations in the US: a genomic analysis of 138 healthy individuals.

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12 December 2020

Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663

1 reference

12 December 2020

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).

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12 December 2020

A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe

1 reference

12 December 2020

Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions

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12 December 2020

Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II

1 reference

12 December 2020

A humanized UGT1 mouse model expressing the UGT1A1*28 allele for assessing drug clearance by UGT1A1-dependent glucuronidation

1 reference

12 December 2020

Cholesterol-lowering effect of ezetimibe in uridine diphosphate glucuronosyltransferase 1A-deficient (Gunn) rats

1 reference

12 December 2020

Ezetimibe: A Selective Cholesterol Absorption Inhibitor

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12 December 2020

Pharmacogenetic impact of polymorphisms in the coding region of the UGT1A1 gene on SN-38 glucuronidation in Japanese patients with cancer.

1 reference

12 December 2020

Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis.

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12 December 2020

UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity

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12 December 2020

Risk factors for severe hyperbilirubinemia in neonates

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12 December 2020

A LC-MS/MS method to quantify the novel cholesterol lowering drug ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1B1.

1 reference

12 December 2020

Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28

1 reference

12 December 2020

Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats

1 reference

12 December 2020

Liquid chromatography-negative ion electrospray tandem mass spectrometry method for the quantification of ezetimibe in human plasma

1 reference

12 December 2020

The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome

1 reference

12 December 2020

Pharmacogenomics of human UDP-glucuronosyltransferase enzymes

1 reference

12 December 2020

10.1007/S00228-010-0899-X

Identifiers

DOI

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6 April 2018

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6 April 2018