(Q51645255)

8 April 2018

title

Novel Pathway for Hypoxia-Induced Proliferation and Migration in Human Mesenchymal Stem Cells: Involvement of HIF-1α, FASN, and mTORC1. (English)

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6

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author name string

Hyun Jik Lee

1

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Jung Min Ryu

2

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Young Hyun Jung

3

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Sang Yub Oh

4

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Sei-Jung Lee

5

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publication date

11 May 2015

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published in

Stem Cells

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volume

33

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issue

7

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page(s)

2182-2195

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Regulation of human placental development by oxygen tension

cites work

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Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

21 January 2018

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Metabolic requirements for the maintenance of self-renewing stem cells

21 January 2018

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Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

21 January 2018

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Metabolic reprogramming by HIF-1 promotes the survival of bone marrow-derived angiogenic cells in ischemic tissue

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The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

21 January 2018

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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 January 2018

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mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

21 January 2018

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Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway

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mTOR and the differentiation of mesenchymal stem cells.

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Mesenchymal stem/progenitor cells developed in cultures from UC blood.

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Human mesenchymal stem cells isolated from the umbilical cord.

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Topical embryonic stem cells enhance wound healing in diabetic rats.

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Redox homeostasis: the linchpin in stem cell self-renewal and differentiation

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Hematopoietic stem cells and their niche.

21 January 2018

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A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche

21 January 2018

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Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

21 January 2018

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Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

21 January 2018

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Elimination of undifferentiated cancer cells by pluripotent stem cell inhibitors

21 January 2018

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Omega-3 and omega-6 fatty acids suppress ER- and oxidative stress in cultured neurons and neuronal progenitor cells from mice lacking PPT1.

21 January 2018

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Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1.

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Hypoxia-inducible factor 2 regulates hepatic lipid metabolism

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Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets

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The involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming

21 January 2018

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Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling

21 January 2018

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mTOR activity under hypoxia

21 January 2018

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Regulation of mTOR and S6K1 activation by the nPKC isoforms, PKCepsilon and PKCdelta, in adult cardiac muscle cells

21 January 2018

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mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k)

21 January 2018

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mTOR phosphorylated at S2448 binds to raptor and rictor

21 January 2018

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Cellular fatty acid metabolism and cancer

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Localization of Fas/CD95 into the lipid rafts on down-modulation of the phosphatidylinositol 3-kinase signaling pathway

21 January 2018

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Defining the role of mTOR in cancer

21 January 2018

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Role of mTOR signaling in tumor cell motility, invasion and metastasis

21 January 2018

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mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways

21 January 2018

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The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

21 January 2018

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RhoA induces MMP-9 expression at CD44 lamellipodial focal complexes and promotes HMEC-1 cell invasion

21 January 2018

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Rho GTPase Rac1 is critical for neutrophil migration into the lung.

21 January 2018

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Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo

21 January 2018

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Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.

21 January 2018

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FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling

21 January 2018

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Off the beaten paths: alternative and crosstalk regulation of Rho GTPases

21 January 2018

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The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade

21 January 2018

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Concise review: Regulation of stem cell proliferation and differentiation by essential fatty acids and their metabolites.

21 January 2018

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Protease-Activated Receptor-1 Antagonist F 16618 Reduces Arterial Restenosis by Down-Regulation of Tumor Necrosis Factor and Matrix Metalloproteinase 7 Expression, Migration, and Proliferation of Vascular Smooth Muscle Cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.2020

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8 April 2018

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8 April 2018