(Q51714832)

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Using protein-ligand docking to assess the chemical tractability of inhibiting a protein target.

scientific article published on 11 March 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 April 2018

http://europepmc.org/abstract/MED/20221654

Using protein-ligand docking to assess the chemical tractability of inhibiting a protein target. (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 April 2018

http://europepmc.org/abstract/MED/20221654

author name string

Richard A Ward

1

1 reference

Europe PubMed Central

PubMed publication ID

10 April 2018

http://europepmc.org/abstract/MED/20221654

publication date

11 March 2010

1 reference

Europe PubMed Central

PubMed publication ID

10 April 2018

http://europepmc.org/abstract/MED/20221654

Journal of Molecular Modeling

1 reference

Europe PubMed Central

PubMed publication ID

10 April 2018

http://europepmc.org/abstract/MED/20221654

16

1 reference

Europe PubMed Central

PubMed publication ID

10 April 2018

http://europepmc.org/abstract/MED/20221654

12

1 reference

Europe PubMed Central

PubMed publication ID

10 April 2018

http://europepmc.org/abstract/MED/20221654

1833-1843

1 reference

Europe PubMed Central

PubMed publication ID

10 April 2018

http://europepmc.org/abstract/MED/20221654

Predicting protein druggability

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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Predicting protein interaction sites: binding hot-spots in protein-protein and protein-ligand interfaces

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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A ‘Rule of Three’ for fragment-based lead discovery?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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The Protein Data Bank

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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High-throughput structural proteomics using x-rays

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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Positioning hydrogen atoms by optimizing hydrogen-bond networks in protein structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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Allosteric inhibition of protein tyrosine phosphatase 1B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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Assessment of programs for ligand binding affinity prediction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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The influence of drug-like concepts on decision-making in medicinal chemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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PTP1B as a drug target: recent developments in PTP1B inhibitor discovery

1 reference

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Identification of compounds with nanomolar binding affinity for checkpoint kinase-1 using knowledge-based virtual screening

1 reference

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New method for fast and accurate binding-site identification and analysis

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Rediscovering the sweet spot in drug discovery.

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

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Between a rock and a hard place?

1 reference

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Crystallographic analysis of triclosan bound to enoyl reductase

1 reference

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The druggable genome

1 reference

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Application of a Theory of Enzyme Specificity to Protein Synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

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Structure-based maximal affinity model predicts small-molecule druggability.

1 reference

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Prodrugs: design and clinical applications.

1 reference

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Druggability indices for protein targets derived from NMR-based screening data

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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Predicting druggable binding sites at the protein-protein interface.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221654

12 December 2020

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Identifiers

10.1007/S00894-010-0683-Y

1 reference

Europe PubMed Central

PubMed publication ID

10 April 2018

http://europepmc.org/abstract/MED/20221654

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 April 2018

http://europepmc.org/abstract/MED/20221654

ResearchGate publication ID

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