(Q51744776)

English

Differential α-synuclein expression contributes to selective vulnerability of hippocampal neuron subpopulations to fibril-induced toxicity.

scientific article published on 3 March 2018

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

Differential α-synuclein expression contributes to selective vulnerability of hippocampal neuron subpopulations to fibril-induced toxicity. (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

1 reference

based on heuristic

inferred from title

author name string

Esteban Luna

1

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

Samantha C Decker

2

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

Dawn M Riddle

3

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

Anna Caputo

4

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

Bin Zhang

5

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

Tracy Cole

6

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

Carrie Caswell

7

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

Sharon X Xie

8

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

Virginia M Y Lee

9

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

Kelvin C Luk

10

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

publication date

3 March 2018

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

Acta Neuropathologica

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

https://scigraph.springernature.com/pub.10.1007/s00401-018-1829-8

0 references

α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration.

1 reference

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Modeling Parkinson's disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain

1 reference

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25 August 2018

α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration.

1 reference

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25 August 2018

Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production.

1 reference

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25 August 2018

α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies

1 reference

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Propagation of pathological α-synuclein in marmoset brain.

1 reference

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25 August 2018

Selective neuronal vulnerability in Parkinson disease

1 reference

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Hippocampal α-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and Is Consistent with Spread of Pathology

1 reference

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25 August 2018

Synucleinopathies: common features and hippocampal manifestations

1 reference

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α-Synuclein-Based Animal Models of Parkinson's Disease: Challenges and Opportunities in a New Era.

1 reference

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25 August 2018

Molecular and Biological Compatibility with Host Alpha-Synuclein Influences Fibril Pathogenicity

1 reference

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25 August 2018

Hipposeq: a comprehensive RNA-seq database of gene expression in hippocampal principal neurons

1 reference

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25 August 2018

Pathological α-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology

1 reference

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Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease

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Leveraging existing data sets to generate new insights into Alzheimer's disease biology in specific patient subsets

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Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons

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Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer's disease

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25 August 2018

Fibril growth and seeding capacity play key roles in α-synuclein-mediated apoptotic cell death

1 reference

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25 August 2018

Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration

1 reference

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25 August 2018

α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation

1 reference

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25 August 2018

Progressive aggregation of alpha-synuclein and selective degeneration of lewy inclusion-bearing neurons in a mouse model of parkinsonism

1 reference

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RNA-Seq data mining: downregulation of NeuroD6 serves as a possible biomarker for alzheimer's disease brains

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25 August 2018

Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes

1 reference

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Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates.

1 reference

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Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson's disease patients

1 reference

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25 August 2018

Pathological alpha-synuclein propagates through neural networks

1 reference

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Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease.

1 reference

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A novel cell migratory zone in the developing hippocampal formation.

1 reference

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25 August 2018

Differential expression of alpha-synuclein in hippocampal neurons

1 reference

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25 August 2018

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.

1 reference

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Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

1 reference

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25 August 2018

A quantitative study of α-synuclein pathology in fifteen cases of dementia associated with Parkinson disease

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Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss

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Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS.

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Advances in the genetics of Parkinson disease

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Calcium entry and α-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons

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Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study

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Prion-like spreading of pathological α-synuclein in brain

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Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

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Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

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Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia.

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In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson's disease

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Direct observation of the interconversion of normal and toxic forms of α-synuclein

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Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

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Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

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Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery

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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

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Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

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Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

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alpha-Synuclein locus triplication causes Parkinson's disease

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Parkinson's disease is associated with hippocampal atrophy

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Astrocytes and Parkinson's disease

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1 reference

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12 December 2020

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10.1007/S00401-018-1829-8

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/29502200

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