(Q51748872)

11 April 2018

title

E6AP promotes the degradation of the PML tumor suppressor. (English)

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11 April 2018

author

Martin Scheffner

10

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11 April 2018

author name string

I Louria-Hayon

1

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11 April 2018

O Alsheich-Bartok

2

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11 April 2018

Y Levav-Cohen

3

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11 April 2018

I Silberman

4

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11 April 2018

M Berger

5

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11 April 2018

T Grossman

6

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11 April 2018

K Matentzoglu

7

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11 April 2018

Y-H Jiang

8

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11 April 2018

S Muller

9

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11 April 2018

S Haupt

11

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11 April 2018

Y Haupt

12

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11 April 2018

publication date

27 March 2009

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11 April 2018

Cell Death & Differentiation

published in

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11 April 2018

volume

16

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11 April 2018

issue

8

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11 April 2018

page(s)

1156-1166

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11 April 2018

https://scigraph.springernature.com/pub.10.1038/cdd.2009.31

exact match

0 references

cites work

Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

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https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

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https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

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https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Loss of the tumor suppressor PML in human cancers of multiple histologic origins

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https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Role of PML and the PML-nuclear body in the control of programmed cell death

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https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Identification of a tumour suppressor network opposing nuclear Akt function

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Review: properties and assembly mechanisms of ND10, PML bodies, or PODs

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

PML nuclear bodies: dynamic sensors of DNA damage and cellular stress

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

PML nuclear bodies and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

PML contributes to a cellular mechanism of repression of herpes simplex virus type 1 infection that is inactivated by ICP0

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

The coiled-coil domain is the structural determinant for mammalian homologues of Drosophila Sina-mediated degradation of promyelocytic leukemia protein and other tripartite motif proteins by the proteasome

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https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

A CK2-dependent mechanism for degradation of the PML tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Identification of three major sentrinization sites in PML

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Differential regulation of sentrinized proteins by a novel sentrin-specific protease

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

The mechanisms of PML-nuclear body formation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RARalpha) and oncogenic RARalpha fusion proteins

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

HPV E6 proteins interact with specific PML isoforms and allow distinctions to be made between different POD structures.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Cloning of the murine homolog of the leukemia-associated PML gene

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Characterization of endogenous human promyelocytic leukemia isoforms

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Ubiquitin and control of transcription

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

PML regulates p53 stability by sequestering Mdm2 to the nucleolus

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Cellular stress and DNA damage invoke temporally distinct Mdm2, p53 and PML complexes and damage-specific nuclear relocalization

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Regulation of turnover of tumor suppressor p53 and cell growth by E6-AP, a ubiquitin protein ligase mutated in Angelman mental retardation syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Decreased expression of e6-associated protein in breast and prostate carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

The function of PML in p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Paternal deletion from Snrpn to Ube3a in the mouse causes hypotonia, growth retardation and partial lethality and provides evidence for a gene contributing to Prader-Willi syndrome

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.31

7 January 2021

Identifiers

DOI

10.1038/CDD.2009.31

1 reference

11 April 2018

Dimensions Publication ID

1007250274

0 references

1 reference

11 April 2018