(Q51764488)

11 April 2018

title

Modification of the duocarmycin pharmacophore enables CYP1A1 targeting for biological activity. (English)

1 reference

11 April 2018

author

Paul M. Loadman

2

1 reference

11 April 2018

Steven D Shnyder

3

1 reference

11 April 2018

Helen M Sheldrake

object named as

Helen M Sheldrake

5

0 references

Klaus Pors

object named as

Klaus Pors

1

0 references

Mark Searcey

object named as

Mark Searcey

9

0 references

author name string

Mark Sutherland

4

1 reference

11 April 2018

Meritxell Guino

6

1 reference

11 April 2018

Konstantinos Kiakos

7

1 reference

11 April 2018

John A Hartley

8

1 reference

11 April 2018

Laurence H Patterson

10

1 reference

11 April 2018

language of work or name

English

0 references

publication date

14 October 2011

1 reference

11 April 2018

published in

Chemical Communications

1 reference

11 April 2018

volume

47

1 reference

11 April 2018

issue

44

1 reference

11 April 2018

page(s)

12062-12064

1 reference

11 April 2018

Regulation, function, and tissue-specific expression of cytochrome P450 CYP1B1.

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Using a combination of cytochrome P450 1B1 and beta-catenin for early diagnosis and prevention of colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Localization of cytochrome P450 CYP2S1 expression in human tissues by in situ hybridization and immunohistochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Cytochrome P450 pharmacogenetics and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Tumour cytochrome P450 and drug activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Mechanisms of in situ activation for DNA-targeting antitumor agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Chemical and biological explorations of the family of CC-1065 and the duocarmycin natural products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

An additional spirocyclization for duocarmycin SA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Synthesis and evaluation of 1,2,8, 8a-Tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one, the parent alkylation subunit of CC-1065 and the duocarmycins: impact of the alkylation subunit substituents and its implications for DNA alkylation catalysi

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Drug resistance reversal--are we getting closer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

DNA sequence selective adenine alkylation, mechanism of adduct repair, and in vivo antitumor activity of the novel achiral seco-amino-cyclopropylbenz[e]indolone analogue of duocarmycin AS-I-145.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Design, synthesis, and evaluation of duocarmycin O-amino phenol prodrugs subject to tunable reductive activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

Selective treatment of hypoxic tumor cells in vivo: phosphate pre-prodrugs of nitro analogues of the duocarmycins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CC15638A

21 January 2018

Identifiers

DOI

10.1039/C1CC15638A

1 reference

11 April 2018

release_dazcdrw2mfeydpjucr5lobknne

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dazcdrw2mfeydpjucr5lobknne

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

11 April 2018