(Q51768954)

11 April 2018

title

Complex pharmacokinetics of a humanized antibody against human amyloid beta peptide, anti-abeta Ab2, in nonclinical species. (English)

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11 April 2018

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Yulia Vugmeyster

1

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11 April 2018

Pam Szklut

2

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11 April 2018

David Wensel

3

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11 April 2018

John Ross

4

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11 April 2018

Xin Xu

5

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11 April 2018

Michel Awwad

6

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11 April 2018

Davinder Gill

7

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11 April 2018

Lioudmila Tchistiakov

8

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11 April 2018

Garvin Warner

9

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11 April 2018

publication date

18 March 2011

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11 April 2018

published in

Pharmaceutical Research

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11 April 2018

volume

28

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11 April 2018

issue

7

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11 April 2018

page(s)

1696-1706

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11 April 2018

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

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Use of quantitative pharmacology in the development of HAE1, a high-affinity anti-IgE monoclonal antibody

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Pharmacokinetics and pharmacodynamics of a new highly secured fibrinogen concentrate

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Metabolism of Fibrinogen in Cirrhosis of the Liver

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Antibodies to the beta-amyloid peptide cross-react with conformational epitopes in human fibrinogen subunits from peripheral blood.

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A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion

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Structural basis for distinctive recognition of fibrinogen γC peptide by the platelet integrin α IIb β 3

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Turnover of radio-iodinated and biosynthetically labelled fibrinogen in rhesus monkeys

21 January 2018

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12 December 2020

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

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12 December 2020

Biodistribution of [125I]-labeled therapeutic proteins: application in protein drug development beyond oncology

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12 December 2020

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

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12 December 2020

Immunotherapy for Alzheimer's disease

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12 December 2020

Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease

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12 December 2020

Metabolism of 131 I-labelled fibrinogen in monkeys infected with Plasmodium coatneyi

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12 December 2020

Disposition of metabolically radiolabeled CE9.1--a macaque-human chimeric anti-human CD4 monoclonal antibody--in transgenic mice bearing human CD4

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12 December 2020

Hematology and serum chemistry parameters in juvenile cynomolgus monkeys (Macaca fascicularis) of Mauritius origin: comparison between purpose-bred and captured animals

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12 December 2020

Is passive immunization for Alzheimer's disease 'alive and well' or 'dead and buried'?

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12 December 2020

TURNOVER AND DISTRIBUTION OF 131-IODINE-LABELLED HUMAN FIBRINOGEN

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12 December 2020

Anti-amyloid-beta immunotherapy in Alzheimer's disease: relevance of transgenic mouse studies to clinical trials.

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12 December 2020

Modulation of fibrin assembly and polymerization by the beta-amyloid of Alzheimer's disease.

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12 December 2020

Prevention and reduction of AD-type pathology in PDAPP mice immunized with A beta 1-42.

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12 December 2020

Transgenic mouse models of Alzheimer's disease

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12 December 2020

10.1007/S11095-011-0405-X

Identifiers

DOI

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11 April 2018

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11 April 2018