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Immunotherapy for Alzheimer's disease
scientific article published on 01 April 2003
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Immunotherapy for Alzheimer's disease
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
main subject
immunotherapy
1 reference
based on heuristic
inferred from title
Alzheimer's disease
1 reference
based on heuristic
inferred from title
author
Harald Hampel
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
Richard Dodel
series ordinal
1
object named as
Richard C Dodel
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
author name string
Yansheng Du
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
publication date
1 April 2003
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
published in
Lancet Neurology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
volume
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
page(s)
215-220
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
cites work
Alzheimer's disease: an overview of current and emerging therapeutic strategies
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
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7 January 2021
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inferred from DOI database lookup
Neuropathological stageing of Alzheimer-related changes
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
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7 January 2021
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Phases of A beta-deposition in the human brain and its relevance for the development of AD.
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7 January 2021
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inferred from DOI database lookup
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
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7 January 2021
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Translating cell biology into therapeutic advances in Alzheimer's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's disease and oxygen radicals: new insights
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
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7 January 2021
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Neurodegenerative disease: amyloid pores from pathogenic mutations
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Beta-secretase as a therapeutic target for inhibitor drugs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
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7 January 2021
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inferred from DOI database lookup
The search for gamma-secretase and development of inhibitors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nasal vaccination with beta-amyloid peptide for the treatment of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
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7 January 2021
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inferred from DOI database lookup
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
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7 January 2021
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inferred from DOI database lookup
Macromolecular permeability across the blood-nerve and blood-brain barriers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid beta peptide as a vaccine for Alzheimer's disease involves receptor-mediated transport at the blood-brain barrier
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor-mediated transport of human amyloid beta-protein 1-40 and 1-42 at the blood-brain barrier
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abeta immunization: moving Abeta peptide from brain to blood
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human antibodies against amyloid beta peptide: a potential treatment for Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disaggregation of Alzheimer beta-amyloid by site-directed mAb.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid-beta immunotherapy for Alzheimer's disease: the end of the beginning
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dosing in phase II trial of Alzheimer's vaccine suspended
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunization with beta-amyloid: could T-cell activation have a harmful effect?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transfected human B cells: a new model to study the functional and immunostimulatory consequences of APP production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
APP peptides stimulate lymphocyte proliferation in normals, but not in patients with Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fc receptors for IgG on cultured human microglia mediate cytotoxicity and phagocytosis of antibody-coated targets.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of prostanoid synthesis in microglial cells and effects of prostaglandin E2 on microglial functions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell mediators of inflammation in the Alzheimer disease brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Call for Elan to publish Alzheimer's trial details.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroinflammation and Alzheimer disease: clinical and therapeutic implications.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced levels of amyloid beta-peptide antibody in Alzheimer disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than healthy elderly individuals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoantibodies to amyloid-beta and Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2803%2900349-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1474-4422(03)00349-1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PubMed publication ID
12849209
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12849209
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12849209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
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