(Q33952134)

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Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

M Koistinaho

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

M Ort

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

J M Cimadevilla

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

R Vondrous

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

B Cordell

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

J Koistinaho

6

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

J Bures

7

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

L S Higgins

8

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

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publication date

27 November 2001

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PubMed publication ID

30 July 2017

98

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

25

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

14675-14680

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Retrograde carbon monoxide is required for induction of long-term potentiation in rat superior cervical ganglion.

1 reference

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Suppression of the induction of long-term depression by carbon monoxide in rat cerebellar slices

1 reference

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Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes

1 reference

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Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease.

1 reference

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5 July 2018

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

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5 July 2018

A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease

1 reference

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Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes.

1 reference

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Transgenic mouse models of Alzheimer's disease

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AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats.

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On the respective roles of nitric oxide and carbon monoxide in long-term potentiation in the hippocampus.

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Translating cell biology into therapeutic advances in Alzheimer's disease

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Alzheimer's disease: genetic studies and transgenic models

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5 July 2018

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

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5 July 2018

3-[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat alpha7 receptors and improves memory-related behaviors in a mecamylamine-sensitive manner

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Exploring the etiology of Alzheimer disease using molecular genetics

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Synaptic currents generated by neuronal acetylcholine receptors sensitive to alpha-bungarotoxin

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Hippocampal synaptic transmission enhanced by low concentrations of nicotine.

1 reference

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5 July 2018

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

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Behavioral and neurophysiological effects of CNS expression of cytokines in transgenic mice

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5 July 2018

Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

5 July 2018

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

5 July 2018

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

5 July 2018

Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human beta-amyloid precursor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

5 July 2018

Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for beta-APP751.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

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Developments of a water-maze procedure for studying spatial learning in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

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The development of the pathologic changes of Alzheimer's disease and senile dementia in patients with Down's syndrome

1 reference

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Expression of the Alzheimer amyloid precursor gene transcripts in the human brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

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Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

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Altered levels of amyloid protein precursor transcripts in the basal forebrain of behaviorally impaired aged rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

5 July 2018

Formation of beta-amyloid protein deposits in brains of transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

5 July 2018

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.

1 reference

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The acute neurotoxicity and effects upon cholinergic axons of intracerebrally injected beta-amyloid in the rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

21 January 2018

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

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Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain.

1 reference

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beta-amyloid: friend or foe.

1 reference

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21 January 2018

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

21 January 2018

Transgenic mouse brain histopathology resembles early Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

21 January 2018

New spatial cognition tests for mice: passive place avoidance on stable and active place avoidance on rotating arenas.

1 reference

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Learning performances, brain NGF distribution and NPY levels in transgenic mice expressing TNF-alpha.

1 reference

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Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

21 January 2018

Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

21 January 2018

Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

21 January 2018

Functional inactivation of dorsal hippocampus impairs active place avoidance in rats.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

21 January 2018

Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

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Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

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Strain dependent and invariant features of transgenic mice expressing Alzheimer amyloid precursor proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

29 October 2018

The neurotoxicity of amyloid beta protein in aged primates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

29 October 2018

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

29 October 2018

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=64740

29 October 2018

Recent work on Alzheimer's disease transgenics

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

21 January 2018

Disease models: relevance is everything

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

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Age-related changes in the density and morphology of plaques and neurofibrillary tangles in Down syndrome brain

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

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beta -Amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261562998

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Animal models of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11724968

12 December 2020

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Identifiers

10.1073/PNAS.261562998

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

2001PNAS...9814675K

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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