(Q51800539)

English

Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H:paraquat oxidoreductase: identification of the enzyme as thioredoxin reductase.

scientific article published on 17 January 2007

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24 December 2019

Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H:paraquat oxidoreductase: identification of the enzyme as thioredoxin reductase (English)

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24 December 2019

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24 December 2019

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24 December 2019

Deborah A Cory-Slechta

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Deborah A Cory-Slechta

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24 December 2019

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Diane E Heck

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24 December 2019

Vladimir Mishin

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24 December 2019

Jun-Yan Hong

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24 December 2019

Mona Thiruchelvam

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24 December 2019

Debra L Laskin

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24 December 2019

Jeffrey D Laskin

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17 January 2007

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24 December 2019

Journal of Biological Chemistry

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24 December 2019

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24 December 2019

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24 December 2019

7939-7949

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24 December 2019

A mechanism of paraquat toxicity involving nitric oxide synthase

1 reference

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21 January 2018

Stimulation by paraquat of microsomal and cytochrome P-450-dependent oxidation of glycerol to formaldehyde

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21 January 2018

Redox cycling of the herbicide paraquat in microglial cultures

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21 January 2018

NADH-dependent generation of reactive oxygen species by microsomes in the presence of iron and redox cycling agents

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21 January 2018

Assessment of lipid peroxidation associated with lung damage induced by oxidative stress in vivo and in vitro studies

1 reference

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21 January 2018

The evolution of free radicals and oxidative stress

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21 January 2018

Redox cycling of radical anion metabolites of toxic chemicals and drugs and the Marcus theory of electron transfer

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21 January 2018

Overview of enzyme systems involved in bio-reduction of drugs and in redox cycling

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21 January 2018

Oxidative stress in the systemic and cellular responses to intermittent hypoxia

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21 January 2018

The action of paraquat and diquat on the respiration of liver cell fractions

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21 January 2018

An assessment of the role of redox cycling in mediating the toxicity of paraquat and nitrofurantoin

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21 January 2018

Deoxyribonucleoside triphosphate pools and growth of glutathione-depleted 3T6 mouse fibroblasts

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21 January 2018

Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation

1 reference

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21 January 2018

Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase

1 reference

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21 January 2018

Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase

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21 January 2018

Methylseleninate is a substrate rather than an inhibitor of mammalian thioredoxin reductase. Implications for the antitumor effects of selenium

1 reference

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21 January 2018

NK-lysin, a disulfide-containing effector peptide of T-lymphocytes, is reduced and inactivated by human thioredoxin reductase. Implication for a protective mechanism against NK-lysin cytotoxicity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611817200

21 January 2018

Effect of genetic variation on human cytochrome p450 reductase-mediated paraquat cytotoxicity

1 reference

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21 January 2018

Development and application of a self-referencing glucose microsensor for the measurement of glucose consumption by pancreatic beta-cells

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21 January 2018

Oxygen consumption oscillates in single clonal pancreatic beta-cells (HIT).

1 reference

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21 January 2018

Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity.

1 reference

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21 January 2018

Does the anaerobic formation of hydroxyl radicals by paraquat monocation radicals and hydrogen peroxide require the presence of transition metals?

1 reference

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21 January 2018

Complexities in horseradish peroxidase-catalyzed oxidation of dihydroxyphenoxazine derivatives: appropriate ranges for pH values and hydrogen peroxide concentrations in quantitative analysis

1 reference

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21 January 2018

Characterization of the oxidase activity in mammalian catalase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611817200

21 January 2018

Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence

1 reference

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21 January 2018

Characterization of hydroxyl radical formation by microsomal enzymes using a water-soluble trap, terephthalate

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21 January 2018

Bipyridylium quaternary salts and related compounds. V. Pulse radiolysis studies of the reaction of paraquat radical with oxygen. Implications for the mode of action of bipyridyl herbicides

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21 January 2018

Inactivation and recovery of nitric oxide synthetic capability in cytokine-induced RAW 264.7 cells treated with "irreversible" NO synthase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611817200

21 January 2018

Characterization of alternative cytosolic forms and cellular targets of mouse mitochondrial thioredoxin reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611817200

21 January 2018

Reactive oxygen species, antioxidants, and the mammalian thioredoxin system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611817200

21 January 2018

Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds

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https://api.crossref.org/works/10.1074%2FJBC.M611817200

21 January 2018

Mitochondrial free radical generation, oxidative stress, and aging

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611817200

21 January 2018

Thioredoxin reductase as a pathophysiological factor and drug target

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611817200

21 January 2018

The accumulation of diamines and polyamines into rat lung slices.

1 reference

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21 January 2018

Development of self-referencing oxygen microsensor and its application to single pancreatic HIT cells: effects of adenylate cyclase activator forskolin on oxygen consumption

1 reference

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21 January 2018

Redox regulation of the hypoxia-inducible factor

1 reference

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21 January 2018

Synergistic interactions between NADPH-cytochrome P-450 reductase, paraquat, and iron in the generation of active oxygen radicals

1 reference

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21 January 2018

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

1 reference

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21 January 2018

NADPH: ferredoxin oxidoreductase acts as a paraquat diaphorase and is a member of the soxRS regulon

1 reference

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21 January 2018

The NADPH: sulfite reductase of Escherichia coli is a paraquat reductase.

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21 January 2018

In vivo oxidation of reduced nicotinamide-adenine dinucleotide phosphate by paraquat and diquat in rat lung

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21 January 2018

Effects of G6PD overexpression in NIH3T3 cells treated with tert-butyl hydroperoxide or paraquat

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21 January 2018

Mechanism of protection of alveolar type II cells against paraquat-induced cytotoxicity by deferoxamine

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21 January 2018

Protective effects of (-)-epigallocatechin gallate and (+)-catechin on paraquat-induced genotoxicity in cultured cells

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21 January 2018

Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols

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21 January 2018

Inhibitory activity of epigallocatechin gallate (EGCg) in paraquat-induced microsomal lipid peroxidation--a mechanism of protective effects of EGCg against paraquat toxicity

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21 January 2018

Paraquat detoxicative system in the mouse liver postmitochondrial fraction

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21 January 2018

Paraquat damage of rat liver mitochondria by superoxide production depends on extramitochondrial NADH

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Loss of activity of the selenoenzyme thioredoxin reductase causes induction of hepatic heme oxygenase‐1

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The thioredoxin system—From science to clinic

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Identifiers

10.1074/JBC.M611817200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17229725%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17229725%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

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