(Q51835357)

13 April 2018

title

Role for p21-activated kinase PAK4 in development of the mammalian heart. (English)

1 reference

13 April 2018

author name string

Tanya Nekrasova

series ordinal

1

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13 April 2018

Audrey Minden

series ordinal

2

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13 April 2018

publication date

16 December 2011

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13 April 2018

published in

Transgenic Research

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13 April 2018

volume

21

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13 April 2018

issue

4

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13 April 2018

page(s)

797-811

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13 April 2018

https://scigraph.springernature.com/pub.10.1007/s11248-011-9578-7

exact match

0 references

cites work

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Direct interaction of p21-activated kinase 4 with PDZ-RhoGEF, a G protein-linked Rho guanine exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Heart development: molecular insights into cardiac specification and early morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Building the mammalian heart from two sources of myocardial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

PAK4 mediates morphological changes through the regulation of GEF-H1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Pak4 induces premature senescence via a pathway requiring p16INK4/p19ARF and mitogen-activated protein kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Genetics of heart development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Incidence of congenital heart disease: I. Postnatal incidence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

The incidence of congenital heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Fgf8 is required for anterior heart field development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

The p21Rac/Cdc42-activated kinases (PAKs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Role of actin polymerization in bending of the early heart tube.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Requirement for neuregulin receptor erbB2 in neural and cardiac development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Targeted disruption of the gene for the PAK5 kinase in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Hsp90 increases LIM kinase activity by promoting its homo-dimerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Embryonic survival and severity of cardiac and craniofacial defects are affected by genetic background in fibroblast growth factor-16 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Cardiac phenotype of mitochondrial creatine kinase knockout mice is modified on a pure C57BL/6 genetic background

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Heart development: learning from mistakes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Multiple essential functions of neuregulin in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

The outflow tract of the heart is recruited from a novel heart-forming field

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

PAK4 is required for regulation of the cell-cycle regulatory protein p21, and for control of cell-cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

PAK4 Kinase Is Essential for Embryonic Viability and for Proper Neuronal Development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Congenital heart malformations: prevalence, severity, survival, and quality of life

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Emerging from the Pak: the p21-activated protein kinase family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Contractility-dependent actin dynamics in cardiomyocyte sarcomeres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Essential role for the Pak4 protein kinase in extraembryonic tissue development and vessel formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Transmembrane neuregulins interact with LIM kinase 1, a cytoplasmic protein kinase implicated in development of visuospatial cognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

PAK4: a pluripotent kinase that regulates prostate cancer cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Genetic pathways to mammalian heart development: Recent progress from manipulation of the mouse genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Isl1Cre reveals a common Bmp pathway in heart and limb development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11248-011-9578-7

Incidence of congenital heart disease: II. Prenatal incidence

21 January 2018

1 reference

12 December 2020

Conotruncal myocardium arises from a secondary heart field

1 reference

12 December 2020

Circulation is established in a stepwise pattern in the mammalian embryo

1 reference

12 December 2020

Heart development in fibronectin-null mice is governed by a genetic modifier on chromosome four

1 reference

12 December 2020

Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation.

1 reference

12 December 2020

The natural history of congenital heart disease in young adults

1 reference

12 December 2020

Rho kinases play an obligatory role in vertebrate embryonic organogenesis

1 reference

12 December 2020

The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis

1 reference

12 December 2020

10.1007/S11248-011-9578-7

Identifiers

DOI

1 reference

13 April 2018

1 reference

13 April 2018