(Q51926084)

English

Kinetic considerations for the quantitative assessment of efflux activity and inhibition: implications for understanding and predicting the effects of efflux inhibition.

scientific article published on 27 December 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 April 2018

http://europepmc.org/abstract/MED/17191095

Kinetic considerations for the quantitative assessment of efflux activity and inhibition: implications for understanding and predicting the effects of efflux inhibition. (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 April 2018

http://europepmc.org/abstract/MED/17191095

author name string

J Cory Kalvass

1

1 reference

Europe PubMed Central

PubMed publication ID

17 April 2018

http://europepmc.org/abstract/MED/17191095

Gary M Pollack

2

1 reference

Europe PubMed Central

PubMed publication ID

17 April 2018

http://europepmc.org/abstract/MED/17191095

publication date

27 December 2006

1 reference

Europe PubMed Central

PubMed publication ID

17 April 2018

http://europepmc.org/abstract/MED/17191095

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

17 April 2018

http://europepmc.org/abstract/MED/17191095

24

1 reference

Europe PubMed Central

PubMed publication ID

17 April 2018

http://europepmc.org/abstract/MED/17191095

2

1 reference

Europe PubMed Central

PubMed publication ID

17 April 2018

http://europepmc.org/abstract/MED/17191095

265-276

1 reference

Europe PubMed Central

PubMed publication ID

17 April 2018

http://europepmc.org/abstract/MED/17191095

Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation

1 reference

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Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.

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The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in mice

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Increased drug delivery to the brain by P-glycoprotein inhibition

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The elementary mass action rate constants of P-gp transport for a confluent monolayer of MDCKII-hMDR1 cells.

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The steady-state Michaelis-Menten analysis of P-glycoprotein mediated transport through a confluent cell monolayer cannot predict the correct Michaelis constant Km.

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Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.

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Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells

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Transport characteristics of fexofenadine in the Caco-2 cell model

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Variable modulation of opioid brain uptake by P-glycoprotein in mice

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21 January 2018

Implications of T-cell P-glycoprotein activity during HIV-1 infection and its therapy

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21 January 2018

Use of loperamide as a phenotypic probe of mdr1a status in CF-1 mice

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21 January 2018

Interaction of cytochrome P450 3A inhibitors with P-glycoprotein

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21 January 2018

Compound profiling for P-glycoprotein at the blood-brain barrier using a microplate screening system

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21 January 2018

Many P-glycoprotein substrates do not inhibit the transport process across cell membranes

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21 January 2018

Modulation of P-glycoprotein Transport Activity in the Mouse Blood-Brain Barrier by Rifampin

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21 January 2018

Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein

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21 January 2018

In vitro substrate identification studies for p-glycoprotein-mediated transport: species difference and predictability of in vivo results

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Overcoming Multidrug Resistance in Cancer: An Update on the Clinical Strategy of Inhibiting P-Glycoprotein

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Impact of P-glycoprotein-mediated intestinal efflux kinetics on oral bioavailability of P-glycoprotein substrates

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Identifiers

10.1007/S11095-006-9135-X

1 reference

Europe PubMed Central

PubMed publication ID

17 April 2018

http://europepmc.org/abstract/MED/17191095

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 April 2018

http://europepmc.org/abstract/MED/17191095

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