(Q51975320)

19 April 2018

title

Regional and cellular distribution of CYP2D subfamily members in rat brain. (English)

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19 April 2018

6

R F Tyndale

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19 April 2018

author name string

S Miksys

1

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19 April 2018

Y Rao

2

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19 April 2018

E M Sellers

3

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19 April 2018

M Kwan

4

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19 April 2018

D Mendis

5

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19 April 2018

language of work or name

English

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publication date

1 June 2000

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19 April 2018

published in

Xenobiotica

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19 April 2018

volume

30

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19 April 2018

issue

6

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19 April 2018

page(s)

547-564

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19 April 2018

Brain mitochondrial cytochromes P450: xenobiotic metabolism, presence of multiple forms and their selective inducibility.

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Purification of multiple forms of cytochrome P450 from a human brain and reconstitution of catalytic activities.

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain.

21 January 2018

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Metabolism of MPTP by cytochrome P4502D6 and the demonstration of 2D6 mRNA in human foetal and adult brain by in situ hybridization.

21 January 2018

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Regional and subcellular distribution of cytochrome P-450-dependent drug metabolism in monkey brain: the olfactory bulb and the mitochondrial fraction have high levels of activity.

21 January 2018

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Genomic cloning and protein expression of a novel rat brain cytochrome P-450 CYP2D18* catalyzing imipramine N-demethylation

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A novel P450 expressed at the high level in rat brain

21 January 2018

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Extrahepatic metabolism of drugs in humans

21 January 2018

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Brain microsomal metabolism of phencyclidine in male and female rats.

21 January 2018

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The rat P450 IID subfamily: complete sequences of four closely linked genes and evidence that gene conversions maintained sequence homogeneity at the heme-binding region of the cytochrome P450 active site

21 January 2018

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The CYP2D gene subfamily: analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats.

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The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms

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The dopamine transporter and cytochrome P45OIID1 (debrisoquine 4-hydroxylase) in brain: resolution and identification of two distinct [3H]GBR-12935 binding proteins.

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Characterization of two P-450 isozymes placed in the rat CYP2D subfamily.

21 January 2018

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Tardive dyskinesia and debrisoquine 4-hydroxylase (CYP2D6) genotype in Japanese schizophrenics.

21 January 2018

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P450 enzymes and Parkinson's disease: the story so far.

21 January 2018

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Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic specificity

21 January 2018

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[3H]GBR-12935 binding to cytochrome P450 in the human brain.

21 January 2018

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Role of P450IID6, the target of the sparteine-debrisoquin oxidation polymorphism, in the metabolism of imipramine

21 January 2018

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Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs.

21 January 2018

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Cytochrome P-450 dependent monooxygenase activity in rat nasal epithelial membranes

21 January 2018

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Cytochromes P-450 in human hepatocyte plasma membrane: recognition by several autoantibodies

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The expression and environmental regulation of P450 enzymes in human placenta

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Debrisoquine hydroxylase gene polymorphism in meningioma

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21 January 2018

Identifiers

DOI

10.1080/004982500406390

1 reference

19 April 2018

PubMed ID

10923858

1 reference

19 April 2018