(Q52060117)

English

Site-directed mutagenesis of the ionizable groups in the active site of Zymomonas mobilis pyruvate decarboxylase: effect on activity and pH dependence.

scientific article published in June 2001

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11422387%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Site-directed mutagenesis of the ionizable groups in the active site of Zymomonas mobilis pyruvate decarboxylase: effect on activity and pH dependence (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11422387%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Zymomonas mobilis

object named as

Zymomonas mobilis

1 reference

based on heuristic

inferred from title

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11422387%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

C Y Huang

1

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8 November 2019

A K Chang

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11422387%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

R G Duggleby

4

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Europe PubMed Central

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8 November 2019

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publication date

1 June 2001

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8 November 2019

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11422387%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

268

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8 November 2019

12

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8 November 2019

3558-3565

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8 November 2019

Sixty years of thiamin diphosphate biochemistry

1 reference

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21 January 2018

High resolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylases

1 reference

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21 January 2018

Structure and properties of pyruvate decarboxylase and site-directed mutagenesis of the Zymomonas mobilis enzyme

1 reference

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21 January 2018

Crystal structure of human branched-chain alpha-ketoacid dehydrogenase and the molecular basis of multienzyme complex deficiency in maple syrup urine disease

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21 January 2018

Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes

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21 January 2018

Crystal structures of the key anaerobic enzyme pyruvate:ferredoxin oxidoreductase, free and in complex with pyruvate

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21 January 2018

The crystal structure of benzoylformate decarboxylase at 1.6 A resolution: diversity of catalytic residues in thiamin diphosphate-dependent enzymes

1 reference

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21 January 2018

The role of residues glutamate-50 and phenylalanine-496 in Zymomonas mobilis pyruvate decarboxylase

1 reference

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21 January 2018

Identification of the catalytic glutamate in the E1 component of human pyruvate dehydrogenase.

1 reference

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21 January 2018

Aspartate-27 and glutamate-473 are involved in catalysis by Zymomonas mobilis pyruvate decarboxylase

1 reference

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21 January 2018

Active site mutants of pyruvate decarboxylase from Zymomonas mobilis--a site-directed mutagenesis study of L112, I472, I476, E473, and N482.

1 reference

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21 January 2018

The role of His113 and His114 in pyruvate decarboxylase from Zymomonas mobilis.

1 reference

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21 January 2018

The Mechanism of Substrate Activation of Pyruvate Decarboxylase: A First Approach

1 reference

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21 January 2018

Substrate activation of brewers' yeast pyruvate decarboxylase is abolished by mutation of cysteine 221 to serine.

1 reference

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21 January 2018

Pyruvate decarboxylase from Zymomonas mobilis. Structure and re-activation of apoenzyme by the cofactors thiamin diphosphate and magnesium ion.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02260.X

21 January 2018

Effects of substitution of aspartate-440 and tryptophan-487 in the thiamin diphosphate binding region of pyruvate decarboxylase from Zymomonas mobilis.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02260.X

21 January 2018

Investigation of the cofactor-binding site of Zymomonas mobilis pyruvate decarboxylase by site-directed mutagenesis

1 reference

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21 January 2018

Thiazolium C(2)-proton exchange: structure-reactivity correlations and the pKa of thiamin C(2)-H revisited

1 reference

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21 January 2018

Origin of the β-Lactam Carbons in Clavulanic Acid from an Unusual Thiamine Pyrophosphate-Mediated Reaction

1 reference

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21 January 2018

A thiamin diphosphate binding fold revealed by comparison of the crystal structures of transketolase, pyruvate oxidase and pyruvate decarboxylase

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02260.X

21 January 2018

How Thiamin Diphosphate Is Activated in Enzymes

1 reference

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21 January 2018

Effects of deletions at the carboxyl terminus of Zymomonas mobilis pyruvate decarboxylase on the kinetic properties and substrate specificity

1 reference

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21 January 2018

Role of Glu51 for Cofactor Binding and Catalytic Activity in Pyruvate Decarboxylase from Yeast Studied by Site-Directed Mutagenesis†

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02260.X

21 January 2018

Mutagenesis at asp27 of pyruvate decarboxylase from Zymomonas mobilis. Effect on its ability to form acetoin and acetolactate

1 reference

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21 January 2018

Is a hydrophobic amino acid required to maintain the reactive V conformation of thiamin at the active center of thiamin diphosphate-requiring enzymes? Experimental and computational studies of isoleucine 415 of yeast pyruvate decarboxylase

1 reference

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21 January 2018

Allosteric properties of yeast pyruvate decarboxylase

1 reference

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21 January 2018

Interdomain information transfer during substrate activation of yeast pyruvate decarboxylase: the interaction between cysteine 221 and histidine 92

1 reference

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21 January 2018

Role of glutamate 91 in information transfer during substrate activation of yeast pyruvate decarboxylase

1 reference

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21 January 2018

Solvent-derived protons in catalysis by brewers' yeast pyruvate decarboxylase

1 reference

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21 January 2018

Buffers of constant ionic strength for studying pH-dependent processes

1 reference

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21 January 2018

Remarkable stabilization of zwitterionic intermediates may account for a billion-fold rate acceleration by thiamin diphosphate-dependent decarboxylases

1 reference

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21 January 2018

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