(Q52324964)

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A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure.

scientific article published in April 2018

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scholarly article

1 reference

Europe PubMed Central

6 July 2018

http://europepmc.org/abstract/PMC/5912948

A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure. (English)

1 reference

Europe PubMed Central

6 July 2018

http://europepmc.org/abstract/PMC/5912948

Francesco Casanova

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Francesco Casanova

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Timothy M Frayling

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Samuel E Jones

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Dereje Jima

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Michael N Weedon

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Michael N Weedon

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Niels Grarup

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Rachel M Freathy

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Rachel M Freathy

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Hanieh Yaghootkar

4

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Hanieh Yaghootkar

1 reference

Europe PubMed Central

6 July 2018

Cecilia Lindgren

20

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Cecilia M Lindgren

1 reference

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6 July 2018

http://europepmc.org/abstract/PMC/5912948

Federico Innocenti

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Federico Innocenti

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Europe PubMed Central

6 July 2018

http://europepmc.org/abstract/PMC/5912948

author name string

Robin N Beaumont

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6 July 2018

http://europepmc.org/abstract/PMC/5912948

Marcus A Tuke

5

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Europe PubMed Central

6 July 2018

http://europepmc.org/abstract/PMC/5912948

Katherine S Ruth

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Europe PubMed Central

6 July 2018

http://europepmc.org/abstract/PMC/5912948

Ben West

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Europe PubMed Central

6 July 2018

http://europepmc.org/abstract/PMC/5912948

Jonathan Locke

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Seth Sharp

10

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6 July 2018

http://europepmc.org/abstract/PMC/5912948

Yingjie Ji

11

1 reference

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http://europepmc.org/abstract/PMC/5912948

William Thompson

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1 reference

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http://europepmc.org/abstract/PMC/5912948

Jamie Harrison

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1 reference

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6 July 2018

http://europepmc.org/abstract/PMC/5912948

Amy S Etheridge

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1 reference

Europe PubMed Central

6 July 2018

http://europepmc.org/abstract/PMC/5912948

Paul J Gallins

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1 reference

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6 July 2018

http://europepmc.org/abstract/PMC/5912948

Fred Wright

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1 reference

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6 July 2018

http://europepmc.org/abstract/PMC/5912948

Yihui Zhou

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1 reference

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6 July 2018

http://europepmc.org/abstract/PMC/5912948

Anna Murray

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http://europepmc.org/abstract/PMC/5912948

Jessica Tyrrell

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6 July 2018

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Andrew R Wood

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publication date

1 April 2018

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6 July 2018

http://europepmc.org/abstract/PMC/5912948

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6 July 2018

http://europepmc.org/abstract/PMC/5912948

23

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6 July 2018

http://europepmc.org/abstract/PMC/5912948

2

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http://europepmc.org/abstract/PMC/5912948

327-336

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6 July 2018

http://europepmc.org/abstract/PMC/5912948

FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Fibroblast growth factor 21 night watch: advances and uncertainties in the field

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.

1 reference

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10 July 2018

Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

FGF21 Regulates Sweet and Alcohol Preference.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

1 reference

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10 July 2018

Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study

1 reference

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10 July 2018

UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age

1 reference

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10 July 2018

Genetic studies of body mass index yield new insights for obesity biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

New genetic loci link adipose and insulin biology to body fat distribution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Defining the role of common variation in the genomic and biological architecture of adult human height

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Discovery and refinement of loci associated with lipid levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Common variants associated with plasma triglycerides and risk for coronary artery disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

FGF21 mimetic shows therapeutic promise.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

FGF21 contributes to neuroendocrine control of female reproduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Novel locus including FGF21 is associated with dietary macronutrient intake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort

1 reference

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10 July 2018

Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Common variants of FUT2 are associated with plasma vitamin B12 levels

1 reference

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10 July 2018

Fibroblast growth factor 21 corrects obesity in mice

1 reference

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Mapping the genetic architecture of gene expression in human liver

1 reference

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The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21.

1 reference

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10 July 2018

FGF-21 as a novel metabolic regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

10 July 2018

Once-weekly administration of a long-acting fibroblast growth factor 21 analogue modulates lipids, bone turnover markers, blood pressure and body weight differently in obese people with hypertriglyceridaemia and in non-human primates.

1 reference

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13 August 2018

A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects

1 reference

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13 August 2018

The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes

1 reference

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13 August 2018

Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma

1 reference

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13 August 2018

Blood Lipids and Type 2 Diabetes Risk: Can Genetics Help Untangle the Web?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5912948

30 November 2018

Statins and type 2 diabetes: genetic studies on target

1 reference

https://pubmed.ncbi.nlm.nih.gov/29641994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of genetically supported target selection on R&D productivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29641994

12 December 2020

based on heuristic

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Identifiers

10.1016/J.CELREP.2018.03.070

1 reference

Europe PubMed Central

6 July 2018

http://europepmc.org/abstract/PMC/5912948

1 reference

Europe PubMed Central

6 July 2018

http://europepmc.org/abstract/PMC/5912948

1 reference

Europe PubMed Central

6 July 2018

http://europepmc.org/abstract/PMC/5912948

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