(Q52407643)

1 May 2018

review article

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title

[Mathematical modeling: an essential tool for the study of therapeutic targeting in solid tumors]. (English)

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1 May 2018

Youcef Mammeri

4

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author name string

Zuzana Saidak

1

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1 May 2018

Anne-Sophie Giacobbi

2

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1 May 2018

Mony Chenda Morisse

3

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1 May 2018

Antoine Galmiche

5

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1 May 2018

language of work or name

French

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publication date

20 December 2017

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1 May 2018

published in

médecine/sciences

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1 May 2018

volume

33

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1 May 2018

issue

12

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1 May 2018

page(s)

1055-1062

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1 May 2018

Somatic mutation in cancer and normal cells

cites work

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Tumors as organs: complex tissues that interface with the entire organism

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

The complexities and versatility of the RAS-to-ERK signalling system in normal and cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

HER2 expression identifies dynamic functional states within circulating breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Models of signalling networks - what cell biologists can gain from them and give to them

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

The dynamic control of signal transduction networks in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

The mathematics of cancer: integrating quantitative models

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Ultrasensitivity in the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Ligand-specific c-Fos expression emerges from the spatiotemporal control of ErbB network dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Mathematical modelling unveils the essential role of cellular phosphatases in the inhibition of RAF-MEK-ERK signalling by sorafenib in hepatocellular carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Network Architecture Predisposes an Enzyme to Either Pharmacologic or Genetic Targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Network quantification of EGFR signaling unveils potential for targeted combination therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Integrating network reconstruction with mechanistic modeling to predict cancer therapies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Information transfer by leaky, heterogeneous, protein kinase signaling systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Frequency modulation of ERK activation dynamics rewires cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Robustness of MEK-ERK Dynamics and Origins of Cell-to-Cell Variability in MAPK Signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Tumour heterogeneity and cancer cell plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

From structure to dynamics: frequency tuning in the p53-Mdm2 network I. Logical approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Boolean ErbB network reconstructions and perturbation simulations reveal individual drug response in different breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Logical Modeling and Dynamical Analysis of Cellular Networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Drug Resistance Mechanisms in Colorectal Cancer Dissected with Cell Type-Specific Dynamic Logic Models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Toward a science of tumor forecasting for clinical oncology

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Network Modeling Identifies Patient-specific Pathways in Glioblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Emergence of drug tolerance in cancer cell populations: an evolutionary outcome of selection, nongenetic instability, and stress-induced adaptation

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

Computational oncology--mathematical modelling of drug regimens for precision medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1051%2FMEDSCI%2F20173312012

10.1051/MEDSCI/20173312012

21 January 2018

Identifiers

DOI

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1 May 2018

0 references

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1 May 2018