(Q38708732)

5 September 2017

Drug Resistance Mechanisms in Colorectal Cancer Dissected with Cell Type-Specific Dynamic Logic Models (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

Bertram Klinger

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

Julio Saez-Rodriguez

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

author name string

Victoria Doldàn-Martelli

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

Thomas Cokelaer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

Anja Sieber

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

Fiona Kogera

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

Mathurin Dorel

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

Mathew J Garnett

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

Nils Blüthgen

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

5 April 2017

1 reference

5 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

volume

77

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

page(s)

3364-3375

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

13 May 2020

cites work

1 reference

12 December 2020

Systems biology and combination therapy in the quest for clinical efficacy.

1 reference

12 December 2020

Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

1 reference

12 December 2020

Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling

1 reference

12 December 2020

Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction

1 reference

12 December 2020

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

1 reference

12 December 2020

Strong negative feedback from Erk to Raf confers robustness to MAPK signalling.

1 reference

12 December 2020

Comparing signaling networks between normal and transformed hepatocytes using discrete logical models

1 reference

12 December 2020

Systematic identification of genomic markers of drug sensitivity in cancer cells

1 reference

12 December 2020

CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms

1 reference

12 December 2020

JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: a rationale for cotargeting these pathways in metastatic breast cancer

1 reference

12 December 2020

The scientific drunk and the lamppost: massive sequencing efforts in cancer discovery and treatment.

1 reference

12 December 2020

Network quantification of EGFR signaling unveils potential for targeted combination therapy.

1 reference

12 December 2020

Computational modeling of ERBB2-amplified breast cancer identifies combined ErbB2/3 blockade as superior to the combination of MEK and AKT inhibitors.

1 reference

12 December 2020

Using network biology to bridge pharmacokinetics and pharmacodynamics in oncology

1 reference

12 December 2020

Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines

1 reference

12 December 2020

Blockade of EGFR and MEK intercepts heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer.

1 reference

12 December 2020

Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.

1 reference

12 December 2020

MEIGO: an open-source software suite based on metaheuristics for global optimization in systems biology and bioinformatics

1 reference

12 December 2020

GSK-3 as potential target for therapeutic intervention in cancer

1 reference

12 December 2020

Combined vemurafenib and cobimetinib in BRAF-mutated melanoma

1 reference

12 December 2020

Improved overall survival in melanoma with combined dabrafenib and trametinib

1 reference

12 December 2020

Pragmatic issues in biomarker evaluation for targeted therapies in cancer

1 reference

12 December 2020

Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer

1 reference

12 December 2020

Angiogenic activity of breast cancer patients' monocytes reverted by combined use of systems modeling and experimental approaches

1 reference

12 December 2020

Reverse engineering of logic-based differential equation models using a mixed-integer dynamic optimization approach

1 reference

12 December 2020

Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in EGFR-Mutant Lung Cancer

1 reference

12 December 2020

Perturbation biology nominates upstream-downstream drug combinations in RAF inhibitor resistant melanoma cells

1 reference

12 December 2020

Inhibition of glycogen synthase kinase-3 beta induces apoptosis and mitotic catastrophe by disrupting centrosome regulation in cancer cells

1 reference

12 December 2020

Discovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical Modeling

1 reference

12 December 2020

The consensus molecular subtypes of colorectal cancer

1 reference

12 December 2020

Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients

1 reference

12 December 2020

A landscape of pharmacogenomic interactions in cancer.

1 reference

12 December 2020

Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells

1 reference

12 December 2020

Perspective: The precision-oncology illusion

1 reference

12 December 2020

Mass-spectrometric exploration of proteome structure and function

1 reference

12 December 2020

OmniPath: guidelines and gateway for literature-curated signaling pathway resources.

1 reference

12 December 2020

Cell-Specific Computational Modeling of the PIM Pathway in Acute Myeloid Leukemia.

1 reference

12 December 2020

Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling.

1 reference

12 December 2020

Determinants of metastatic competency in colorectal cancer

1 reference

12 December 2020

The Heterocellular Emergence of Colorectal Cancer

1 reference

12 December 2020

Colorectal Cancer Subtypes: Developmental Origin and Microenvironmental Regulation

1 reference

12 December 2020

Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells.

1 reference

12 December 2020

10.1158/0008-5472.CAN-17-0078

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6433282&resulttype=core&format=json

13 May 2020

1 reference