(Q52530011)

English

Contribution of the murine mdr1a P-glycoprotein to hepatobiliary and intestinal elimination of cationic drugs as measured in mice with an mdr1a gene disruption.

scientific article published in April 1998

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scholarly article

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

Contribution of the murine mdr1a P-glycoprotein to hepatobiliary and intestinal elimination of cationic drugs as measured in mice with an mdr1a gene disruption. (English)

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

Michael Müller

3

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

author name string

Smit JW

1

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

Schinkel AH

2

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

Weert B

4

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

Meijer DK

5

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

language of work or name

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publication date

1 April 1998

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

27

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

1056-1063

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

4

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

ABC Transporters: From Microorganisms to Man

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A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

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The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues

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Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

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Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein

1 reference

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

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Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers

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Structure-pharmacokinetics relationship of quaternary ammonium compounds. Correlation of physicochemical and pharmacokinetic parameters.

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Structure-pharmacokinetics relationship of quaternary ammonium compounds

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Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

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Specificity of transporters for 'organic anions' and 'organic cations' in the kidney

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H+-gradient-dependent active transport of tetraethylammonium cation in apical-membrane vesicles isolated from kidney epithelial cell line LLC-PK1.

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Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice

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MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring

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Drug excretion mediated by a new prototype of polyspecific transporter

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Multispecific amphipathic substrate transport by an organic anion transporter of human liver.

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Genetic analysis of renal function in mice. 1. Glomerular filtration rate and its correlation with body and kidney weight

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Carrier-mediated transport in the hepatic distribution and elimination of drugs, with special reference to the category of organic cations

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21 January 2018

Effect of procainamide on renal tubular transport of cimetidine in the isolated perfused rat kidney

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21 January 2018

Transport of procainamide in a kidney epithelial cell line LLC-PK1.

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21 January 2018

Effects of membrane potential versus pHi on the cellular retention of doxorubicin analyzed via a comparison between cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance (MDR) transfectants

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The role of the MDR protein in altered drug translocation across tumor cell membranes

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The ABC of channel regulation

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P-glycoprotein and cell volume-activated chloride channels

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21 January 2018

Hepatic transport systems regulating pHi, cell volume, and bile secretion

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510270422

21 January 2018

Inhibition of intestinal P-glycoprotein and effects on etoposide absorption.

1 reference

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21 January 2018

Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510270422

21 January 2018

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

1 reference

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21 January 2018

Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510270422

21 January 2018

ATP-dependent transport of amphiphilic cations across the hepatocyte canalicular membrane mediated by mdr1 P-glycoprotein

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510270422

7 January 2021

based on heuristic

inferred from DOI database lookup

Hepatic uptake and biliary excretion of organic cations--I. Characterization of three new model compounds

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510270422

7 January 2021

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Investigations on the hepatic uptake systems for organic cations with a photoaffinity probe of procainamide ethobromide

1 reference

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7 January 2021

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Assay of vecuronium in plasma using solid-phase extraction, high-performance liquid chromatography and post-column ion-pair extraction with fluorimetric detection

1 reference

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7 January 2021

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Uptake and excretion of vecuronium bromide and pancuronium bromide in the isolated perfused rat liver

1 reference

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7 January 2021

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Transport interactions of different organic cations during their excretion by the intact rat kidney

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510270422

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of hepatic P-glycoprotein enhances biliary excretion of vincristine in rats

1 reference

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7 January 2021

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Intestinal absorption barriers and transport mechanisms, including secretory transport, for a cyclic peptide, fibrinogen antagonist

1 reference

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7 January 2021

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Identifiers

10.1002/HEP.510270422

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/9537446

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