(Q52565016)

3 May 2018

title

Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes. (English)

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3 May 2018

4

Denis Duboule

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3 May 2018

1

François Spitz

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3 May 2018

Carole Herkenne

2

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3 May 2018

Michael A Morris

series ordinal

3

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3 May 2018

language of work or name

English

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publication date

3 July 2005

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3 May 2018

published in

Nature Genetics

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3 May 2018

volume

37

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3 May 2018

issue

8

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3 May 2018

page(s)

889-893

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3 May 2018

https://scigraph.springernature.com/pub.10.1038/ng1597

exact match

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cites work

The evolutionary dynamics of eukaryotic gene order

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7 January 2021

Long-range control of gene expression: emerging mechanisms and disruption in disease

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A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly

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7 January 2021

A global control region defines a chromosomal regulatory landscape containing the HoxD cluster

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7 January 2021

Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression

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7 January 2021

Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations

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7 January 2021

Vertebrate hox gene regulation: clustering and/or colinearity?

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7 January 2021

Hox and HOM: homologous gene clusters in insects and vertebrates

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7 January 2021

Engineering chromosomal rearrangements in mice

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7 January 2021

Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum

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7 January 2021

Cre-loxP-mediated inactivation of the alpha6A integrin splice variant in vivo: evidence for a specific functional role of alpha6A in lymphocyte migration but not in heart development.

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7 January 2021

Abrogation of experimental colitis correlates with increased apoptosis in mice deficient for CD44 variant exon 7 (CD44v7).

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7 January 2021

Serial deletions and duplications suggest a mechanism for the collinearity of Hoxd genes in limbs.

1 reference

7 January 2021

Targeted inversion of a polar silencer within the HoxD complex re-allocates domains of enhancer sharing.

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7 January 2021

Absence of radius and ulna in mice lacking hoxa-11 andhoxd-11

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7 January 2021

Hox gene expression in teleost fins and the origin of vertebrate digits

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7 January 2021

The murine and Drosophila homeobox gene complexes have common features of organization and expression.

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7 January 2021

Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns.

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7 January 2021

Elements both 5' and 3' to the murine Hoxd4 gene establish anterior borders of expression in mesoderm and neurectoderm.

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7 January 2021

Engineering mouse chromosomes with Cre-loxP: range, efficiency, and somatic applications

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7 January 2021

Normal cardiovascular development in mice deficient for 16 genes in 550 kb of the velocardiofacial/DiGeorge syndrome region

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7 January 2021

Control of colinearity in AbdB genes of the mouse HoxD complex.

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7 January 2021

Engineering chromosomes in mice through targeted meiotic recombination (TAMERE)

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7 January 2021

An enhancer-titration effect induces digit-specific regulatory alleles of the HoxD cluster.

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7 January 2021

Rapid and efficient detection of transgene homozygosity by FISH of mouse fibroblasts.

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7 January 2021

A t(2;8) balanced translocation with breakpoints near the human HOXD complex causes mesomelic dysplasia and vertebral defects.

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7 January 2021

Identifiers

DOI

10.1038/NG1597

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3 May 2018

PubMed ID

15995706

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3 May 2018