(Q52608158)

4 May 2018

title

Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease. (English)

1 reference

4 May 2018

RELA proto-oncogene, NF-kB subunit

main subject

NF-κB

0 references

1 reference

positive regulation of amyloid-beta formation

GOA release 2020-03-11

1 reference

V-rel reticuloendotheliosis viral oncogene homolog A (avian)

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Yigang Tong

8

1 reference

4 May 2018

Weihong Song

9

1 reference

4 May 2018

author name string

Chia-Hsiung Chen

1

1 reference

4 May 2018

Weihui Zhou

2

1 reference

4 May 2018

Shengchun Liu

3

1 reference

4 May 2018

Yu Deng

4

1 reference

4 May 2018

Fang Cai

5

1 reference

4 May 2018

Masahide Tone

6

1 reference

4 May 2018

Yukiko Tone

7

1 reference

4 May 2018

publication date

18 February 2011

1 reference

4 May 2018

The International Journal of Neuropsychopharmacology

published in

1 reference

4 May 2018

volume

15

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4 May 2018

issue

1

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4 May 2018

page(s)

77-90

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4 May 2018

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1

cites work

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Translational regulation of BACE-1 expression in neuronal and non-neuronal cells

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Transgenic murine cortical neurons expressing human Bcl-2 exhibit increased resistance to amyloid beta-peptide neurotoxicity

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Differential utilization of upstream AUGs in the beta-secretase mRNA suggests that a shunting mechanism regulates translation

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Degradation of BACE by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Control of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Expression of the Alzheimer protease BACE1 is suppressed via its 5'-untranslated region

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Alteration of transcription factors NF-kappaB and STAT1 in Alzheimer's disease brains.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Structure, regulation and function of NF-kappa B

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasis

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Immortalized fibroblasts from NF-kappaB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor alpha after transformation by v-Ras

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Leaky scanning and reinitiation regulate BACE1 gene expression

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

SP1 regulates a human SNAP-25 gene expression.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to beta-amyloid peptides

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Ibuprofen decreases cytokine-induced amyloid beta production in neuronal cells.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Bcl-2 expression in thalamus, brainstem, cerebellum and visual cortex of adult primate.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Oxidative stress potentiates BACE1 gene expression and Abeta generation

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Function and activation of NF-kappa B in the immune system

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

The role of Sp1 and NF-kappa B in regulating CD40 gene expression

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Enhancement of immunoreactivity for NF-kappa B in the hippocampal formation and cerebral cortex of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Increased BACE1 maturation contributes to the pathogenesis of Alzheimer's disease in Down syndrome.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review)

1 reference

https://api.crossref.org/works/10.1017%2FS1461145711000149

7 January 2021

10.1017/S1461145711000149

Identifiers

DOI

1 reference

4 May 2018

1 reference

4 May 2018