(Q52646109)

14 June 2018

title

PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT. (English)

1 reference

14 June 2018

author name string

Wen-Kai Shi

1

1 reference

14 June 2018

Xiao-Dong Zhu

2

1 reference

14 June 2018

Cheng-Hao Wang

3

1 reference

14 June 2018

Yuan-Yuan Zhang

4

1 reference

14 June 2018

Hao Cai

5

1 reference

14 June 2018

Xiao-Long Li

6

1 reference

14 June 2018

Man-Qing Cao

7

1 reference

14 June 2018

Shi-Zhe Zhang

8

1 reference

14 June 2018

Kang-Shuai Li

9

1 reference

14 June 2018

Hui-Chuan Sun

10

1 reference

14 June 2018

publication date

20 March 2018

1 reference

14 June 2018

published in

Cell Death and Disease

1 reference

14 June 2018

volume

9

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14 June 2018

issue

4

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14 June 2018

page(s)

428

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14 June 2018

Creative Commons Attribution 4.0 International

copyright license

start time

20 March 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Role of Akt/PKB and PFKFB isoenzymes in the control of glycolysis, cell proliferation and protein synthesis in mitogen-stimulated thymocytes

14 June 2018

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Blockage of glycolysis by targeting PFKFB3 suppresses tumor growth and metastasis in head and neck squamous cell carcinoma

14 June 2018

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14 June 2018

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AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest

14 June 2018

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6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27

14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases

14 June 2018

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14 June 2018

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Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.

14 June 2018

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Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer

14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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14 June 2018

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High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers

14 June 2018

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Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial

14 June 2018

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An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect

14 June 2018

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Mechanism of open complex and dual incision formation by human nucleotide excision repair factors

14 June 2018

1 reference

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Drug resistance and DNA repair

14 June 2018

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14 June 2018

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Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861039

MicroRNA-26a inhibits angiogenesis by down-regulating VEGFA through the PIK3C2α/Akt/HIF-1α pathway in hepatocellular carcinoma

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861039

TGF-β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861039

Akt mediates TIGAR induction in HeLa cells following PFKFB3 inhibition.

13 August 2018

1 reference

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P48 is a predictive marker for outcome of postoperative interferon-alpha treatment in patients with hepatitis B virus infection-related hepatocellular carcinoma.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861039

13 August 2018

Hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5861039

Positive serum hepatitis B e antigen is associated with higher risk of early recurrence and poorer survival in patients after curative resection of hepatitis B-related hepatocellular carcinoma

30 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41419-018-0435-Y

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41419-018-0435-Y

1 reference

14 June 2018

PMC publication ID

5861039

1 reference

14 June 2018

PubMed publication ID

29559632

1 reference

14 June 2018