(Q47915386)

6 February 2018

http://europepmc.org/abstract/MED/28834297

title

TGF-β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells (English)

1 reference

6 February 2018

http://europepmc.org/abstract/MED/28834297

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Anna Manzano

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jose Luis Rosa

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Aurea Navarro-Sabaté

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Esther Castaño

6

0 references

Francesc Ventura

object named as

Francesc Ventura

9

0 references

Ramon Bartrons

11

object named as

Ramon Bartrons

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Ana Rodríguez-García

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Paula Samsó

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Helga Simon-Molas

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Ubaldo Martinez-Outshoorn

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

English

0 references

publication date

20 August 2017

1 reference

6 February 2018

http://europepmc.org/abstract/MED/28834297

published in

FEBS Journal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

3437-3454

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Non-Smad Signaling Pathways of the TGF-β Family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Differentiation plasticity regulated by TGF-beta family proteins in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Cellular context-dependent "colors" of transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Partners in crime: the TGFβ and MAPK pathways in cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Non-Smad TGF-beta signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

TGFβ signalling in context

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

TGF-beta signaling in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Transforming growth factor-beta-mediated autocrine growth regulation of gliomas as detected with phosphorothioate antisense oligonucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Expression of TGF-beta isoforms, TGF-beta receptors, and SMAD molecules at different stages of human glioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Transforming Growth Factor (TGF)-β Promotes de Novo Serine Synthesis for Collagen Production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

The cancer cell 'energy grid': TGF-β1 signaling coordinates metabolism for migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Metabolic reprogramming of cancer-associated fibroblasts by IDH3α downregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

TGF-β-induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Transforming growth factor-β induced Warburg-like metabolic reprogramming may underpin the development of peritoneal endometriosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

On the Origin of Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Insulin induces PFKFB3 gene expression in HT29 human colon adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Overexpression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4 in the human breast and colon malignant tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Human placental fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase: its isozymic form, expression and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Molecular cloning, expression, and chromosomal localization of a ubiquitously expressed human 6-phosphofructo-2-kinase/ fructose-2, 6-bisphosphatase gene (PFKFB3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Characterization of a new liver- and kidney-specific pfkfb3 isozyme that is downregulated by cell proliferation and dedifferentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is up-regulated in high-grade astrocytomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Interleukin 6 enhances glycolysis through expression of the glycolytic enzymes hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Cooperation of adenosine with macrophage Toll-4 receptor agonists leads to increased glycolytic flux through the enhanced expression of PFKFB3 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Akt-dependent activation of the heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) isoenzyme by amino acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Cross-talk between Smad and p38 MAPK signalling in transforming growth factor beta signal transduction in human glioblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

TGF-β and Smad3 modulate PI3K/Akt signaling pathway in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

SMAD and p38 MAPK signaling pathways independently regulate alpha1(I) collagen gene expression in unstimulated and transforming growth factor-beta-stimulated hepatic stellate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Transcriptional cross-talk between Smad, ERK1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-beta-induced aggrecan gene expression in chondrogenic ATDC5 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Myostatin regulates cardiomyocyte growth through modulation of Akt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase-3 is required for transforming growth factor β1-enhanced invasion of Panc1 cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Role of PFKFB3-driven glycolysis in vessel sprouting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

Techniques to monitor glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14201

21 January 2018

Identifiers

DOI

10.1111/FEBS.14201

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28834297%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference