(Q52650208)

5 May 2018

title

Cell competition is a tumour suppressor mechanism in the thymus. (English)

1 reference

5 May 2018

author

Benedikt Brors

9

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5 May 2018

Vera C Martins

object named as

Vera C Martins

1

0 references

Sergey E. Mastitsky

object named as

Sergey E Mastitsky

8

0 references

Hans-Reimer Rodewald

12

object named as

Hans-Reimer Rodewald

1 reference

5 May 2018

author name string

Katrin Busch

2

1 reference

5 May 2018

Dilafruz Juraeva

3

1 reference

5 May 2018

Carmen Blum

4

1 reference

5 May 2018

Carolin Ludwig

5

1 reference

5 May 2018

Volker Rasche

6

1 reference

5 May 2018

Felix Lasitschka

7

1 reference

5 May 2018

Thomas Hielscher

10

1 reference

5 May 2018

Hans Joerg Fehling

11

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5 May 2018

language of work or name

English

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publication date

14 May 2014

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5 May 2018

published in

Nature

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5 May 2018

volume

509

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5 May 2018

issue

7501

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5 May 2018

page(s)

465-470

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5 May 2018

https://scigraph.springernature.com/pub.10.1038/nature13317

exact match

0 references

cites work

Competitive interactions between cells: death, growth, and geography

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21 January 2018

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Mechanisms of cell competition: themes and variations

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Irradiation selects for p53-deficient hematopoietic progenitors.

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p53-mediated hematopoietic stem and progenitor cell competition.

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Relative fitness of hematopoietic progenitors influences leukemia progression.

21 January 2018

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Thymus-grafted SCID mice show transient thymopoiesis and limited depletion of V beta 11+ T cells

21 January 2018

1 reference

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Thymus-autonomous T cell development in the absence of progenitor import

21 January 2018

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Thymocytes may persist and differentiate without any input from bone marrow progenitors

21 January 2018

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Acute lymphoblastic leukaemia

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

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Hematopoietic stem cell transplantation without irradiation.

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The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers

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Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

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The TLX1 oncogene drives aneuploidy in T cell transformation

21 January 2018

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Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

21 January 2018

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Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

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Activating Notch1 mutations in mouse models of T-ALL.

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Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma

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Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia

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Rag-dependent and Rag-independent mechanisms of Notch1 rearrangement in thymic lymphomas of Atm(-/-) and scid mice.

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Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1.

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Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis.

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Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.

21 January 2018

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Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants

21 January 2018

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Distinct regions of the interleukin-7 receptor regulate different Bcl2 family members

21 January 2018

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Inactivation of the Cdkn2a locus cooperates with HMGA1 to drive T-cell leukemogenesis

21 January 2018

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Roles of HMGA proteins in cancer

21 January 2018

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Is normal hematopoiesis maintained solely by long-term multipotent stem cells?

21 January 2018

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 January 2018

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The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal

21 January 2018

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The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas

21 January 2018

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21 January 2018

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Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

21 January 2018

1 reference

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Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13317

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13317

T cell receptor antagonist peptides induce positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13317

Pro-Thymocyte Expansion by c-kit and the Common Cytokine Receptor γ Chain Is Essential for Repertoire Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13317

Continued RAG expression in late stages of B cell development and no apparent re-induction after immunizion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13317

Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24828041

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE13317

1 reference

5 May 2018

Dimensions Publication ID

1053567433

0 references

1 reference

5 May 2018